Frequency and predictors of cholesterol target attainment in patients with stable coronary heart disease in Belgium: results from the Dyslipidemia International Study II (DYSIS II ).

: To document the frequency and predictors of low-density lipoprotein cholesterol (LDL-C) target value attainment among patients with coronary heart disease (CHD) in Belgium. : The second Dyslipidemia International Study (DYSIS II) was an observational study of the prevalence of dyslipidemias and lipid target value attainment. Patients in this analysis were aged ≥ 18, had documented CHD, and had a full lipid profile.

Heat shock induces thermotolerance and inhibition of lysis in a lysogenic strain of Lactococcus lactis.

In this preliminary work, the heat shock response of lactic acid bacteria was investigated and characterized. Log-phase Lactococcus lactis cells pre-incubated at 40 degrees C before heat challenge at 52 degrees C for 30 min demonstrated increased thermotolerance as compared with cells pre-incubated at 30 degrees C. The response persisted for at least 60 min.

Response of Lactococcus (Streptococcus) lactis to N-methyl-N'-nitro-N-nitrosoguanidine: absence of adaptive response.

Pretreatment of cells of Lactococcus lactis subsp. lactis with low levels of N-methyl-N'-nitro-N-nitrosoguanidine does not reduce the cytotoxic and mutagenic effects caused by high concentration of this agent. This observation indicates that there is no efficient inducible error-free repair system for alkylation damage similar to the 'adaptive response' described in detail for Escherichia coli.

Mutagenesis in Streptococcus lactis exposed to UV irradiation and alkylating agents.

The lethal and mutagenic effects of various mutagens on three strains of Streptococcus lactis were investigated. Lethality studies demonstrated that S. lactis was relatively sensitive to UV irradiation, methyl methanesulphonate (MMS) and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), and, to a lesser extent, to ethyl methanesulphonate (EMS).