The role of uterine closure in the risk of uterine rupture.

Objective: To evaluate the effects of prior single-layer compared with double-layer closure on the risk of uterine rupture.

Methods: A multicenter, case-control study was performed on women with a single, prior, low-transverse cesarean who experienced complete uterine rupture during a trial of labor. For each case, three women who underwent a trial of labor without uterine rupture after a prior low-transverse cesarean delivery were selected as control participants.