Publications by authors named "Gill Rooney"

Article Synopsis
  • Women at high risk for venous thromboembolism during and after pregnancy are recommended pharmacological prophylaxis, but determining who should receive it involves weighing various factors, which currently lacks clarity in the UK.
  • The study aims to measure decision uncertainty regarding thromboprophylaxis selection for pregnant women and proposes future research to alleviate that uncertainty, while ensuring it’s practical and acceptable to patients and healthcare providers.
  • A decision-analytic model revealed variable risk assessment model outcomes with significant biases, indicating a need for more focused future studies to improve decision-making in thromboprophylaxis use.
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Objectives: To assess the comparative accuracy of risk assessment models (RAMs) to identify women during pregnancy and the early postnatal period who are at increased risk of venous thromboembolism (VTE).

Design: Systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Data Sources: MEDLINE, Embase, Cochrane Library and two research registers were searched until February 2021.

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Background: Chronic kidney disease-associated pruritus (CKD-aP) is a common and burdensome condition for end-stage kidney disease (ESKD) patients, especially those receiving haemodialysis. High-quality evidence of the relationship between CKD-aP and health-related quality of life (HRQoL) can therefore inform clinicians and policymakers about treatment choice and reimbursement decisions.

Methods: A systematic literature review and narrative synthesis stratified by study design and HRQoL instrument was conducted to evaluate in adult ESKD patients receiving in-centre haemodialysis the relationship between CKD-aP and HRQoL assessed using multi dimensional generic or condition-specific preference- or non-preference-based measures.

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Objective: To identify the most appropriate patient reported outcome measure (PROM) to quantify anxiety of participants in the United Kingdom (UK) National Abdominal Aortic Aneurysm Screening Programme (NAAASP).

Methods: Comprehensive electronic searches were undertaken to identify studies reporting development or validation of PROMs used in the measurement of anxiety in screened populations. Study selection, data extraction and analysis were conducted independently by two reviewers; the "COnsensus-based Standards for the selection of health Measurement INstruments" (COSMIN) classification of measurement properties was used in the evaluation of included PROMs enabling a recommendation to be made for the most appropriate PROM for use in the NAAASP.

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