A synthesis of [ C]formamidine acetate.

The one-step synthesis of [ C]formamidine acetate from [ C]barium cyanamide is described with product characterization by TLC and proton NMR.

Tritium labelling of two potent dopamine D receptor agonists at high specific activity.

An efficient method is described to radiolabel several dopamine D receptor agonists with tritium at high specific activity.

Beta-C-mannosides as selectin inhibitors.

Potential E- and P-selectin inhibitors were synthesized to explore a hydrophobic area on the E-selectin surface and the PSGL-1 protein binding site on the P-selectin surface that was recently defined by crystallography. Three series of mannose-based compounds (libraries A, B, and C) were synthesized using solution phase parallel synthesis. Biological evaluation of these compounds was done using two ELISA-based assays and transferred NOE (trNOE) experiments.