Anosognosia in Amnestic Mild Cognitive Impairment Is Related to Diminished Hippocampal Volume Comparable to Alzheimer's Disease Dementia: Preliminary MRI Findings.

Although the presence of anosognosia in amnestic mild cognitive impairment (aMCI) may be predictive of conversion to Alzheimer's disease (AD), little is known about its neural correlates in AD and aMCI. Four different groups were compared using volumetric and diffusion magnetic resonance imaging metrics in regions of interest (hippocampus and cingulum cortex gray matter, cingulum bundle white matter): aMCI subjects with anosognosia ( = 6), aMCI subjects without anosognosia ( = 12), AD subjects with anosognosia ( = 6), and AD subjects without anosognosia ( = 9). aMCI subjects with anosognosia displayed a significantly lower gray matter density (GMD) in the bilateral hippocampus than aMCI subjects without anosognosia, which was accounted for by bilateral hippocampal differences.

[Descriptive epidemiology and frequency variations of astrocytic tumors in the National Institute of Neurology and Neurosurgery of Mexico].

Objective: To determine distribution, localization and frequency variations of astrocytic tumors (AT) in a Mexican Institute of neurology.

Materials And Methods: Institutional registries of AT from five decades were analyzed. AT/ Surgical discharges (SD) and AT/Central Nervous System Tumors (CNST) from 1995 to 2014 were compared.

[Validation of a cutoff point for the short version of the Depression Scale of the Center for Epidemiologic Studies in older Mexican adults].

Objective: To identify a valid cutoff point associated with Center for Epidemiologic Studies, Depression Scale (CES-D) of seven items, which allows the classification of older adults according to presence/absence of clinically significant depressive symptoms.

Materials And Methods: Screening study with 229 older adults residing in two states of Mexico (Morelos and Tlaxcala), which were part of the sample from the National Survey of Health and Nutrition, 2012. We estimated the sensitivity and specificity associated with the selected cutoff points using the diagnostic criteria of ICD-10 (International Classification of Diseases, 10th revision) and DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth edition).

[Neuropsychiatric symptoms in older adults with dementia and their relationship to disease severity].

Unlabelled: Neuropsychiatric symptoms are the psychopathological dimension of dementia and they integrate a set of symptoms among those are: personality, behavioral and basic functions changes.

Objective: To analyze the prevalence of neuropsychiatric symptoms in elder people diagnosed with dementia, the association of symptoms with each other, their relationship with the severity of the disease and the stress generated by them in caregivers.

Material And Methods: Secondary data analysis of 180 cases diagnosed with dementia from a population-based cross-sectional study of 2,003 older adults living in rural and urban areas of low to medium income in Mexico.