Publications by authors named "Gilberto A Jimenez-Castillo"

Background: Cognitive impairment is twice more frequent in elderly with type 2 diabetes mellitus (DM). This study was conducted to determine the association between glycemic control and cognitive performance among community-dwelling elderly persons in Mexico.

Methods: Cross-sectional study conducted in individuals aged 60 years or elderly participating in the 2012 Mexican Health and Aging Study.

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Background: It has been proposed that Vitamin D helps reduce the accumulation of cerebral β-amyloid-42 by innate immune stimulation and phagocytosis activation. An association between low Vitamin D levels and Alzheimer's dementia (AD) has been established. We determined the association between Vitamin D, mild cognitive impairment (MCI), and AD in older Mexican adults (> 65 years).

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Article Synopsis
  • Frailty, which makes older adults more vulnerable, may contribute to worsening vascular dementia, specifically in those with vascular-type mild cognitive impairment (MCIv).* -
  • A study assessed 180 participants divided into four groups, revealing that the mixed group (frail + MCIv) was older, had lower education levels, and exhibited worse cognitive performance and reduced blood flow in the brain.* -
  • Key factors associated with the mixed group included age, diabetes prevalence, and higher scores on the Geriatric Depression Scale, indicating that frailty is linked to poorer cognitive function and health outcomes.*
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