Next-day residual effects of hypnotics in DSM-IV primary insomnia: a driving simulator study with simultaneous electroencephalogram monitoring.

Rationale: Most studies that investigated the next-day residual effects of hypnotic drugs on daytime driving performances were performed on healthy subjects and after a single drug administration.

Objectives: In the present study, we further examine whether the results of these studies could be generalised to insomniac patients and after repeated drug administration.

Method: Single and repeated (7 day) doses of zolpidem (10 mg), zopiclone (7.