Reductive effect of ursodeoxycholic acid on bilirubin levels in neonates on phototherapy.

Background: Phototherapy is paramount in the management of high total serum bilirubin (TSB). Whether its effectiveness can be improved with ursodeoxycholic acid (UDCA) has not been evaluated among newborns of African descent.

Methods: A double-blind-controlled study was used to evaluate the effect of UDCA on the management of high TSB in neonates.