Retinal age as a predictive biomarker of the diabetic retinopathy grade.

Objective: To apply artificial intelligence (AI) techniques, through deep learning algorithms, for the development and optimization of a system for predicting the age of a person based on a color retinography and to study a possible relationship between the evolution of retinopathy diabetes and premature ageing of the retina.

Methods: A convolutional network was trained to calculate the age of a person based on a retinography. Said training was carried out on a set of retinographies of patients with diabetes previously divided into three subsets (training, validation and test).

Fotopic and scotopic retinal sensitivity and foveal fixation normal values using microperimetry in healthy population.

Purpose: To determine normal values of fotopic and scotopic retinal sensitivity and foveal fixation obtained by microperimetry, using MP3-S microperimeter (Nidek, Gamagori, Japan), in a healthy population.

Methods: Observational, crossectional, single centre study. Fotopic and scotopic microperimetry was performed using with a customized 13-point fovea-centered pattern in healthy volunteers without ocular pathology.

[A protocol for the treatment of retinopathy of prematurity in Spain].

Objective: To prepare a protocol for the treatment of retinopathy of prematurity (ROP) agreed by the majority of Spanish ophthalmologists dedicated to this topic.

Material And Method: A draft of the protocol was produced taking into account the experience of the participants and up to date publications. This draft was corrected by all the ophthalmologists participating in the project, and the final document was agreed by all of them.

Screening program for retinopathy of prematurity in Spain.

Objective: To prepare a retinopathy of prematurity (ROP) screening program as agreed by most of Spanish ophthalmologists dedicated to this topic.

Materials And Methods: A draft of the protocol was produced taking into account the experience of the participants and current publications. This draft was corrected by all the ophthalmologists participating in the project and the final document produced was agreed by all of them.

[Macular hole and Alport's syndrome].

Case Report: We present the clinical cases of two male patients of 38 and 39 years, diagnosed with Alport's syndrome, who suffered a bilateral macular hole and a giant unilateral macular hole with retinal thinning in the other eye, respectively.

Discussion: Alport's syndrome is a genetic disorder characterised by mutation of genes encoding type IV collagen, the main component of the internal limiting membrane, a structure identified in basal membrane of the retinal pigment epithelium-Brüch's membrane complex. This alteration can influence the predisposition to macular holes.

[Guidelines of clinical practice of the SERV (Spanish Retina and Vitreous Society): management of ocular complications of diabetes. Diabetic retinopathy and macular oedema].

Objective: Diabetes mellitus is considered the most common cause of blindness in the working population of industrialized countries, with diabetic macular edema being the most common cause of decreased visual acuity and proliferative diabetic retinopathy (PDR) being responsible for the most severe visual deficits. We have therefore tried to establish a guide for clinical intervention whose purpose is to provide orientation on the treatment of diabetic retinopathy and its complications. This is necessary at a time when many treatment options have emerged whose role is not yet fully defined.

[Ischemic anterior syndrome and intraocular calcification].

Objective/methods: We report the case of a sixty-year-old female that following retinal detachment surgery in her left eye, presented with a clinical picture that initially was misdiagnosed as endophthalmitis.

Results/conclusions: The patient suffered an anterior ischemic syndrome secondary to the retinal surgery, and accidentally, the presence of an intraocular calcification was discovered. We study the influence of the osteoblastic neoformation in the ischemic process.

[Doppler ultrasound in type I diabetes: preliminary results].

Purpose: To study the differences of blood flow in type I diabetes patients using a color Doppler ultrasound.

Material And Methods: We measured the systolic peak velocity (Vmax), diastolic velocity (Vmin) as well as the resistance index in the central retinal artery (CRA) and in the ophthalmic artery (OA) using a color Doppler ultrasound in 40 diabetic patients. We classified the patients according to the duration of diabetes, which ranged from 1 to 28 years.