Effects of Struthanthus venetus methanol extract in the guinea pig heart.

Struthanthus venetus (Sv) from family Loranthaceae is employed in traditional medicine to treat coughs. In previous studies, a methanol extract of Sv shows hypotensive effects and changes in heart rate in rats. The purpose of this study was to determine the effect of a methanol extract of Sv on the electrocardiogram (EKG), and histological changes in the guinea pig heart.

Effect of lithium chloride on the anaphylactic response of smooth muscle.

Lithium chloride (LiCl) is used for treatment of viral diseases, anxiety, depressive maniac disorder and experimental allergic encephalomyelitis. Lithium has also been shown to exert an effect on elements of the immune system. The aim of this work was to study the effect of a single dose of LiCl on the anaphylactic sensitized response in vitro from guinea pig aortic rings.

Lead acetate action on anaphylactic response of guinea pig smooth muscle.

Experiments were performed to evaluate lead acetate effects on the anaphylactic contraction in guinea pigs smooth muscles. Aortic rings from guinea pigs exposed to lead acetate developed an anaphylactic contraction significantly lower than the contraction induced by the antigen in controls. In the smooth muscle of the intestine, lead acetate did not modify the anaphylactic response.

Effect of stress on the Schultz-Dale reaction in guinea pig aorta.

The smooth muscle of thoracic aorta from guinea pig sensitized with egg albumin (EA) produced an anaphylactic contraction when it was exposed to EA. Experiments were performed to evaluate stress effects on the anaphylactic contraction in guinea pig aortic rings. Two types of stressors were used as immunosuppressor stimuli: physical restraint and shaking of the animals.

Vasoconstrictor effect of Cissus sicyoides on guinea-pig aortic rings.

1. The effect of the aqueous extract of Cissus sicyoides (CS) on isolated guinea pig aortic rings was studied. CS contracts the smooth muscle of the aorta in a dose-response relation.

Actions of perezone on rat smooth muscle.

1. Perezone (PZN) on the in vitro intestinal smooth muscle of the rat relaxes the basal tonus of the smooth muscle, interrupts spontaneous activity and also blocks the contractile response induced by ACh, K+, and Ba2+; these actions are dose dependent. 2.

Influence of formamide on the electrical and mechanical properties of the guinea pig ventricle.

1. Guinea pig papillary muscle in vitro upon exposure of Formamide (FMD) exerts a dose dependent positive inotropic effect. 2.

Effect of the length of degenerating phrenic nerve fibres on the anaphylactic contraction of the diaphragm.

1. The effect of denervation on the anaphylactic contraction of the diaphragm from actively sensitized guinea pig has been studied. 2.

Anaphylactic reaction in smooth muscle from the duck.

1. To know if the absence of desensitization in the chicken is characteristic of avian tissues, we studied the anaphylactic reaction in the duck. The contractions elicited in pieces of small intestine of actively immunized ducks upon exposure to the specific antigen, or Schultz-Dale reaction, were compared to similar responses of sensitized chicken and guinea pig intestine.

Ca2+-agonistic effects of diazepam, a benzodiazepine 1-4 derivative, on isolated mouse and guinea pig left atria.

In normal Krebs solution, diazepam (1.75X10(-4) M) increased the action potential duration in a reversible form and caused a positive inotropic effect on mouse auricular muscle (4). 2.

Anaphylactic contraction of guinea pig smooth muscle passively sensitized with chicken antiserum.

1. Actively sensitized guinea pig intestine responds, typically, with a large contraction to the first application of antigen (Ag). This is followed by a spontaneous relaxation of the tissue, while still in the presence of the Ag and a rapid desensitization, i.

Non-desensitizing in vitro anaphylactic reaction of chicken visceral muscle.

1. The contractions elicited in pieces of small intestine of actively immunized young chickens upon exposure to the specific antigen (Ag), or Schultz-Dale reaction, have been compared to similar responses of sensitized guinea-pig intestine. 2.

Mechanism of the schultz-dale reaction in the denervated diaphragmatic muscle of the Guinea pig.

The mechanism of the contractions elicited by specific antigens in immunologically sensitized muscle tissue (Schultz-Dale responses) has been investigated on single fibers of denervated guinea pig hemidiaphragms. This preparation can be either actively or passively allergized, showing Schultz-Dale responses similar to those of visceral muscle. Specific antigens were applied with an electrically operated microtap to discrete areas of the cell surface while recording the electrical activity with intracellular microelectrodes.