Publications by authors named "Gift Nwanne"

Article Synopsis
  • Cutaneous mycobacterial infections are hard to diagnose and treat, but understanding the skin's immune response could lead to new therapies.
  • A study with 10 participants injected them with Mycobacterium bovis and examined immune responses through blood tests and skin biopsies over time.
  • Findings showed early systemic immune responses and revealed significant interactions between various skin cell types, indicating that nonimmune cells play a role in how the skin responds to mycobacterial infections.
View Article and Find Full Text PDF
Article Synopsis
  • Homeless shelter residents and staff are potentially at a higher risk for SARS-CoV-2 infection, but previous estimates were mainly based on limited data from specific outbreaks.
  • A study conducted in King County, Washington, from January 2020 to May 2021 involved routine surveillance and outbreak testing in 23 shelters, collecting over 12,000 samples from nearly 3,000 participants.
  • Results showed 4.74 infections per 100 individuals, with most cases being asymptomatic and detected during routine testing; vaccinated individuals and current smokers had lower infection rates, emphasizing the need for continuous surveillance in these settings.
View Article and Find Full Text PDF

Background: Persons experiencing homelessness face increased risk of influenza as overcrowding in congregate shelters can facilitate influenza virus spread. Data regarding on-site influenza testing and antiviral treatment within homeless shelters remain limited.

Methods: We conducted a cluster-randomized stepped-wedge trial of point-of-care molecular influenza testing coupled with antiviral treatment with baloxavir or oseltamivir in residents of 14 homeless shelters in Seattle, WA, USA.

View Article and Find Full Text PDF

Background: In HIV programs, mentor mothers (MMs) are women living with HIV who provide peer support for other women to navigate HIV care, especially in the prevention of mother-to-child transmission of HIV (PMTCT). Nigeria has significant PMTCT program gaps, and in this resource-constrained setting, lay health workers such as MMs serve as task shifting resources for formal healthcare workers and facility-community liaisons for their clients. However, challenging work conditions including tenuous working relationships with healthcare workers can reduce MMs' impact on PMTCT outcomes.

View Article and Find Full Text PDF

Introduction: The period of transition from pediatric to adult care has been associated with poor health outcomes among 10-19 year old adolescents living with HIV (ALHIV). This has prompted a focus on the quality of transition services, especially in high ALHIV-burden countries. Due to lack of guidelines, there are no healthcare transition standards for Nigeria's estimated 240,000 ALHIV.

View Article and Find Full Text PDF