Publications by authors named "Giedre Herrerias"
Clinical factors associated with severity in patients with inflammatory bowel disease in Brazil based on 2-year national registry data from GEDIIB.
Sci Rep
February 2024
Article Synopsis
- The Brazilian Organization for Crohn's Disease and Colitis (GEDIIB) created a national registry to study factors linked to the severity of inflammatory bowel disease (IBD) among Brazilian patients.
- The study included 1,179 patients, primarily diagnosed with ulcerative colitis (UC) or Crohn's Disease (CD), and found that many had extensive disease, with a significant portion needing biologic treatments.
- Factors like age, disease extent, and certain complications increased the severity of IBD, particularly for those with extensive colitis or specific disease behaviors.
Background: Inflammatory bowel diseases (IBDs) are chronic diseases that demand continuous interaction between patients and healthcare providers. Quality of care (QoC) is a factor that contributes to a patient's adherence to treatment and its success.
Aim: To evaluate QoC in patients from a single IBD reference center.
Clinical and Psychological Factors Associated with Addiction and Compensatory Use of Facebook Among Patients with Inflammatory Bowel Disease: A Cross-Sectional Study.
Int J Gen Med
February 2022
Background: Inflammatory bowel diseases are chronic conditions characterized by incapacitating symptoms, which can compromise patient's quality of life and social interaction. As social media use is continuously increasing and Facebook is one of the most accessed social media worldwide, this study aimed to evaluate the use of Facebook and identify clinical and psychological factors associated with addiction and compensatory use among patients.
Methods: This case-control study enrolled 100 outpatients and 100 healthy individuals, who were classified into the patient and control groups, respectively.
Management of inflammatory bowel disease and serum level of infliximab in newborn exposed to anti-TNF therapy during pregnancy: Case report and literature review.
Medicine (Baltimore)
December 2021
Rationale: Heightened inflammatory bowel disease (IBD) activity during pregnancy is associated with higher rates of preterm birth, miscarriage, and low birth weight. Therefore, its adequate treatment is essential, considering the risk-benefit of medication use. Although previous literature has described the management of IBD during pregnancy, few studies have assessed the pharmacokinetics of IBD drugs in the newborn.
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- - The IBD National Patient Registry, initiated by GEDIIB, aims to collect data on Inflammatory Bowel Disease (IBD) patients in Brazil to improve diagnosis and treatment access, enhancing overall patient care and quality of life.
- - A cohort study was conducted from July 2020 to August 2021, involving 797 patients with either Crohn's Disease (CD) or Ulcerative Colitis (UC), obtaining data primarily from medical records and patient visits.
- - Results showed a mean patient age of 44.75 years, with 60% diagnosed with UC, 52.9% from university hospitals, and significant data on disease symptoms, onset age, and classifications of CD and UC types
Article Synopsis
- - The study investigates the prevalence of hepatic diseases in patients with Inflammatory Bowel Disease (IBD), including Crohn's Disease (CD) and Ulcerative Colitis (UC), highlighting that these patients are prone to liver issues like non-alcoholic fatty liver disease (NAFLD) and cirrhosis.
- - Conducted in Brazil, the research utilized a cross-sectional approach, gathering clinical, demographic, and ultrasound data from 71 IBD patients, mostly of middle age and predominantly women.
- - Findings revealed that 45.07% of the patients had NAFLD of varying severity, and a significant correlation was noted between liver steatosis and characteristics of liver morphology on ultrasound.
Background: Inflammatory Bowel Disease (IBD) is an inflammatory and chronic disease, as well as non-alcoholic fatty liver disease (NAFLD). Current literature has shown that IBD patients are at high risk for NAFLD. In those patients, the pathogenesis of NAFLD may be more complex and related to multifactor causes, such as gut dysbiosis, unhealthy nutritional behavior, body composition and systemic inflammation.
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- Adalimumab is a treatment for moderate-to-severe Crohn's disease but can trigger reactivation of latent infections like tuberculosis (TB).
- A case study of a 38-year-old patient revealed that after starting adalimumab, he developed pulmonary TB despite initial tests showing no latent infection.
- The report emphasizes the need for proper screening and monitoring for tuberculosis in patients undergoing anti-TNF therapy to prevent serious health complications.