Novel application of cytodetachment technology to the analysis of dental implant surfaces.

Purpose: The present study introduced the application of cytodetachment technology--the examination of single cell responses to implant material surfaces--to the analysis of implant surfaces with a view to significantly improving upon conventional methods of studying cell interactions with implant surfaces.

Materials And Methods: With the new cytodetachment technology, osteoblasts (MG-63) were allowed to attach to a surface, and a nanoprobe was positioned adjacent to the cell. The probe was then moved using a piezo-actuator to completely detach the cell.