Depletion-Induced Self-Assembly of Colloidal Particles on a Solid Substrate.

We investigate the depletion contributions to the self-assembly of microcolloids on solid substrates. The assembly is driven by the exclusion of nanoparticles and nonadsorbing polymers from the depletion zone between the microcolloids in the liquid and the underlying substrate. The model system consists of 1 μm polystyrene particles that we deposit on a flat glass slab in an electrolyte solution.

Particle Network Self-Assembly of Similar Size Sub-Micron Calcium Alginate and Polystyrene Particles Atop Glass.

Particle-mediated self-assembly, such as nanocomposites, microstructure formation in materials, and core-shell coating of biological particles, offers precise control over the properties of biological materials for applications in drug delivery, tissue engineering, and biosensing. The assembly of similar-sized calcium alginate (CAG) and polystyrene sub-micron particles is studied in an aqueous sodium nitrate solution as a model for particle-mediated self-assembly of biological and synthetic mixed particle species. The objective is to reinforce biological matrices by incorporating synthetic particles to form hybrid particulate networks with tailored properties.

Bioequivalence studies of cetirizine tablets using the urine excretion data of healthy Ghanaian male volunteers.

Background: In the wake of economic challenges, the role of generic medicines has become crucial in meeting the healthcare needs of people. Their use, however, can only be guaranteed if established to be bioequivalent to their corresponding innovator products.

Aim: In this study, we assess the suitability of a generic brand of cetirizine hydrochloride tablet to be used in place of the innovator brand on the Ghanaian market through bioequivalence assessment.