Comparison of Mold Populations in Water-Damaged Homes in Australia and the United States.

The goal of this study was to examine whether the Environmental Relative Moldiness Index (ERMI) scale created for United States (U.S.) homes was applicable in the assessment of mold contamination for Australian homes.

Effect of proteasome inhibitor 1 on wound healing: a potential scar prevention therapy.

Unlabelled: In vitro and in vivo assessments suggest that proteasome inhibitors may be useful for modulating wound healing.

Methods: Proteasome Inhibitor I was used to assess the potential utility of proteasome inhibitors in improving wound healing in a standard rat model. Bilateral, 6 cm incisions were made 1 cm lateral to the spine of adult male Sprague Dawley rats.

Transdermal lovastatin enhances fracture repair in rats.

Statins have been shown to stimulate BMP2 transcription and bone formation. This raises the possibility that they could be useful for enhancing rates of fracture repair. Observational studies in patients treated with oral statins for lipid-lowering have been controversial.

Proteasome inhibitors stimulate both bone formation and hair growth by similar mechanisms.

We propose that the remodeling process that occurs in localized areas on endosteal bone surfaces and in Haversian canals shares many features in common with the mammalian hair cycle. In both, there are phases of resorption or regeneration, a transition phase, and then a phase of growth, termed anagen in the hair follicle, and formation in the bone remodeling cycle. Furthermore, we suggest that these processes both use the same molecular mechanisms, and specifically the Hedgehog-BMP-Wnt signal transduction cascades.