Publications by authors named "Gianni Dall'ara"

Article Synopsis
  • A case of ventricular thrombosis linked to myocarditis from immune checkpoint inhibitors (ICIs) presented as a myocardial infarction and worsened by severe cardiogenic shock.
  • The rare occurrence of intraventricular thrombus formation in ICI-related myocarditis complicates diagnosis, particularly when distinguishing it from tumor masses in cancer patients.
  • Effective diagnosis requires thorough clinical assessment and advanced imaging techniques, as cardiovascular complications from ICIs, though infrequent, can have high mortality rates.
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Background: Intramyocardial dissecting haematoma (IDH) is a rare life-threatening event usually complicating an acute myocardial infarction. Poor data exist about diagnosis, management, and outcome.

Case Summary: We reported a case of giant IDH managed conservatively, thanks to stable clinical status and haemodynamics, which evolved towards resorption.

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Patients suffering from coronavirus disease-19 (COVID-19)-related interstitial pneumonia have variable outcomes, and the risk factors for a more severe course have yet to be comprehensively identified. Cohort studies have suggested that coronary artery calcium (CAC), as estimated at chest computed tomography (CT) scan, correlated with patient outcomes. However, given that the prevalence of CAC is gender- and age-dependent, the influence of baseline confounders cannot be completely excluded.

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Takotsubo syndrome (TTS) is a clinical syndrome characterized by a transient left ventricular dysfunction whose diagnosis can be challenging due to its resemblance to acute myocardial infarction (AMI). Despite the growing recognition of TTS, acute complications and long-term mortality rates are comparable to those observed in AMI patients. In this context, a systematic diagnostic approach is imperative for an accurate patient assessment, with due consideration of the distinctive characteristics and optimal timing of each imaging modality.

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Background: There is little data on the outcome of balloon aortic valvuloplasty (BAV) in relation to valve dimensions and calcification patterns. The procedure is not standardized, particularly the choice of balloon size.

Methods: This retrospective multicenter study focused on BAV efficacy and safety by analyzing the relationship between balloon size, annulus geometry (i.

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Takotsubo syndrome (TTS) is a rare disease mimicking acute coronary syndrome, often triggered by physical or emotional stress, and characterized by transient left ventricular dysfunction. Recurrences are described in about 5% of cases and may have different clinical and imaging patterns. In the present report, SARS-COV-2 infection, even in the absence of symptoms and overt emotional stress, seems correlated with recurrence of TTS, due to the absence of other recognized triggers.

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Postpartum electrical storm due to torsade de pointes is a rare but life-threatening condition. The uniqueness of this case lies in the use of cabergoline to suppress postpartum ventricular arrhythmias in absence of heart disease. Timely multidisciplinary management is crucial to achieve final diagnosis, deliver proper treatment and improve prognosis.

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Article Synopsis
  • The resorbable magnesium scaffold (RMS) is being studied for its safety and long-term effectiveness in patients undergoing bioresorbable scaffold implantation, amid conflicting results from earlier research.
  • In a multicenter study in Italy, 543 patients were followed for a minimum of one year, with strict criteria for patient selection and RMS implantation techniques.
  • Results showed a low occurrence of serious complications at one year, with 3.5% of patients experiencing major adverse events, suggesting that RMS is a safe option that could lead to renewed interest in scaffold technology if further confirmed by randomized trials.
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Left main coronary artery percutaneous coronary intervention is particularly complex when stenting across the distal bifurcation is required in the presence of a diameter mismatch between the proximal main and distal branches. A suboptimal procedural result increases the risk of thrombosis and restenosis. Considering the paucity of data published on this topic, our objective was to provide technical solutions to deal with this complex anatomy.

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Rapid and systematic access to coronary angiography (CAG) and target temperature management (TTM) might improve outcome in comatose patients who survive cardiac arrest (CA). However, there is controversy around indicating immediate CAG in the absence of transmural ischemia on the electrocardiogram after return of spontaneous circulation (ROSC). We evaluated the short- and long-term outcome of patients undergoing systematic CAG and TTM, based on whether culprit lesion percutaneous coronary intervention (PCI) was performed.

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Introduction: Balloon aortic valvuloplasty (BAV) improves hemodynamic and clinical status of patients with severe aortic stenosis (AS) for a limited period of 6-12 months. However, there is a high number of procedures performed worldwide and an upward trend over the last decades.

Areas Covered: Epidemiology of AS and the advent of transcatheter aortic valve implantation (TAVI) contribute to the extensive referral of patients.

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In patients with severe calcified coronary lesions, angioplasty procedures are associated with significant technical problems and a higher rate of complications. Nowadays, intravascular lithotripsy represents a safe and effective system for the treatment of calcified coronary stenosis before stent deployment. In this article, we report three complex clinical or angiographic cases in which the use of coronary lithotripsy is not yet codified.

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Article Synopsis
  • The study aimed to evaluate the safety and feasibility of mini-invasive radial balloon aortic valvuloplasty (BAV), along with its effects on quality of life and frailty in patients undergoing transcatheter aortic valve implantation (TAVI).
  • A total of 330 patients were included, with BAV performed successfully in 314, showing no major bleeding and a minor bleeding rate of 1.8%; both quality of life and frailty improved noticeably after 30 days.
  • The findings indicated that patients who improved their frailty status had better long-term survival rates after TAVI, while those with persistent frailty had significantly worse outcomes.
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Purulent pericarditis is rare and usually associated with pneumonia, bacteremia, immunosuppression, and thoracic surgery. A timely diagnostic pericardiocentesis with dedicated maneuvers to improve the effectiveness of drainage and pericardial fibrinolytic rinsing can improve prognosis and prevent a surgical pericardiectomy. Imaging offers useful clues for a more aggressive approach.

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Article Synopsis
  • Balloon aortic valvuloplasty (BAV) is considered a useful option for certain patients with severe aortic stenosis, serving as a bridge to surgery or TAVI, or as a trial for unclear symptoms.
  • * International guidelines endorse BAV for various roles, including as a palliative measure to enhance quality of life for those unable to undergo surgery.
  • * Recent technical advancements in BAV procedures have reduced complications and improved outcomes, particularly through minimally invasive methods.
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Objectives: To assess the incidence of no-reflow in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI), analyze possible causes and differential diagnoses, and identify useful management approaches.

Methods: In this multicenter observational study, all CTO-PCIs performed between January 2018 and April 2019 were reviewed to collect no-reflow complications, defined as Thrombolysis in Myocardial Infarction (TIMI) flow ≤1 in a patent epicardial artery. Patient clinical, anatomical, and procedural characteristics were analyzed.

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A 31-year-old man with Noonan syndrome who suffered an out-of-hospital cardiac arrest presented at our institution with severe postanoxic coma (Glasgow coma scale 3), but normalized electrocardiogram and stable hemodynamics. Coronary angiography documented a giant right coronary artery supplying collateral flow to the left coronary artery, which presented a left main functional occlusion.

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The recommended treatment for ST-segment elevation myocardial infarction (STEMI) is primary percutaneous coronary intervention (pPCI). However, in a non-negligible proportion of patients, pPCI is ineffective and the cardiologist must face the decision of how to achieve optimal myocardial reperfusion. Although the possibility of a rescue fibrinolytic strategy has not been evaluated yet in this clinical setting, it is a viable alternative to emergency cardiac surgery.

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