Publications by authors named "Gianna Calimano"
Biology (Basel)
October 2024
Article Synopsis
- - Women can develop hypertension during the transition to menopause, with animal studies showing this condition linked to changes in NMDA receptors in the brain region responsible for regulating blood pressure.
- - Using an accelerated ovarian failure model, researchers discovered that hypertensive peri-menopausal female mice had higher levels of a crucial NMDA receptor subunit (GluN1) in the cytoplasm compared to male mice.
- - Activation of estrogen receptor beta (ERß) in peri-menopausal females not only diminished hypertension but also increased the presence of GluN1 in the cell membranes, unlike in male mice where ERß activation had no effect on blood pressure or GluN1 levels.
