Publications by authors named "Gianluca Fadda"

Article Synopsis
  • A study investigated weight changes in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) receiving Dupilumab therapy, focusing on the link between weight gain and improved sense of smell over a year.
  • Results showed significant weight gain and olfactory improvement in patients who had mild smell dysfunction or normal smell before treatment, while those with complete loss of smell did not experience significant weight changes.
  • The findings suggest that improvements in nasal function from the treatment may impact weight, but further research is needed to clarify the relationship between olfactory changes and weight regulation in CRSwNP patients.
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Background: Obstructive sleep apnea (OSA) is a prevalent sleep disorder characterized by repeated episodes of partial or complete obstruction of the upper airway during sleep. While the systemic implications of OSA are well documented, the dental consequences are less frequently discussed yet equally significant. This review aims to elucidate the oral health impacts of OSA, emphasizing the importance of interdisciplinary care.

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Background: To compare the functional and anatomical results of two different types of grafts in type 1 tympanoplasty (TPL I). Methods: A retrospective comparative bicentric study was conducted on patients treated with TPL I using temporal fascia or tragal cartilage. We evaluated the functional and anatomical results with intergroup and intragroup analyses.

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Background: to evaluate the residual rate and the functional results after ten years from canal wall down tympanoplasty (CWD) for tympano-mastoid cholesteatoma. Methods: All the patients undergoing CWD for chronic otitis media with cholesteatoma at our ENT University Department between January 2002 and December 2022 were initially assessed. We performed clinical and diagnostic evaluation at baseline, 6 months, and then every year until an average follow-up of 10 years was obtained.

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Chronic rhinosinusitis (CRS) is one of the most frequent comorbidities associated with asthma and it contributes to an amplified global disease burden in asthmatics. CRS prevalence is much higher in asthmatic patients compared to the general population and it is more frequently related to severe asthma, especially in presence of nasal polyps (chronic rhinosinusitis with nasal polyps, CRSwNP). Moreover, asthma exacerbation has a higher occurrence in CRSwNP.

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Introduction: Isolated sphenoid sinus inflammatory diseases (ISSIDs) are responsible for about 75% of isolated sphenoid sinus opacifications. Computer tomography (CT) and magnetic resonance imaging (MRI) should be used in a complementary manner for the assessment of ISSIDs. This evaluation sheds some light on the extent of disease and intracranial and intra-orbital involvement.

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Article Synopsis
  • A 59-year-old man with acute myeloid leukemia developed rhino-orbital-cerebral mucormycosis shortly after a stem cell transplant.
  • He received prompt antifungal treatment and underwent endoscopic sinus surgery, which led to resolution of the infection.
  • Monitoring the drug isavuconazole during treatment indicated a link between its plasma levels and improvement in intestinal graft-versus-host disease (GvHD), suggesting the importance of drug monitoring in similar cases.
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Introduction: Paranasal sinus fungus ball (PSFB) is a non-invasive mycosis, which appears in immunocompetent patients, along with unilateral lesion. The purpose of this study was to analyse various symptoms of PSFB and its radiological, pathological, and microbiological findings. In addition, this study involved the investigation of the incidence of bacterial coinfection and surgical techniques applied for this infection and to report the modern developments in this domain.

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Background: This study evaluates the diagnostic role of preoperative cytology of parotid neoplasms. The method is particularly useful in the evaluation of the parotid diseases in which the same clinical features may be treated variously. Fine-needle aspiration biopsy is a simple and well-tolerated diagnostic tool, which provides accurate information for diagnosis and follow-up of the disease.

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