Publications by authors named "Giancarlo Perferi"
Article Synopsis
- - T1DM (Type 1 Diabetes Mellitus) is the most common type of diabetes in children, influenced by genetic, environmental, and immune factors, particularly linked to specific HLA gene haplotypes.
- - The study analyzed 165 Italian children with T1DM, comparing their HLA types to a control group of 819 healthy individuals to investigate genetic associations with the disease.
- - Results indicated that the haplotypes DR3DQ2 and DR4DQ8 significantly increase T1DM risk, with the newly identified haplotype DRB1 * 04: 05-DQA1 * 03-DQB1 * 02 also presenting a potential link to the disease onset among the studied population.
Background: Nut allergies are an increasingly frequent health issue in the pediatric population. Tree nuts (TN) and peanuts are the second cause of food anaphylaxis in Italy. Unfortunately, knowledge of the clinical characteristics of a TN allergy in Italian children is limited.
View Article and Find Full Text PDFNasal Swab as Preferred Clinical Specimen for COVID-19 Testing in Children.
Pediatr Infect Dis J
September 2020
The first pediatric study demonstrating significantly higher positivity rate of nasal (mid-turbinate) swab testing over oropharyngeal swab testing in detecting SARS-CoV-2 (Fisher exact test 0.046, Cohen K 0.43, confidence interval 95%, 0.
View Article and Find Full Text PDFUnlabelled: Genetic variability related to the host immune system has been proposed as one of the most influential factors in the development of diseases caused by HPV.
Clinical Case: We report the case of a 5-year-old child in whom chronic laryngeal papillomatosis, probably acquired vertically during labor, was detected. The diagnosis of laryngeal papillomatosis was confirmed with a biopsy after a first surgery to remove the papillomas.
Background: A higher prevalence of coeliac disease (CD) has been reported in patients with Williams-Beuren syndrome (WBS), though coexistence with other autoimmune diseases has not been evaluated.
Objective: The aim of this study was to examine the prevalence of the more frequent autoimmune diseases and organ- and non-organ specific autoantibodies in WBS.
Methods: We longitudinally analysed 46 WBS patients to evaluate the prevalence and co-occurrence of the major autoantibodies and HLA typing for CD diagnosis.