Publications by authors named "Gian Maria Giamporcaro"
Impaired exocrine pancreatic function in different stages of type 1 diabetes.
BMJ Open Diabetes Res Care
February 2021
Article Synopsis
- The study aimed to explore the pancreatic exocrine function in type 1 diabetes (T1D) patients using various non-invasive tests.
- It included adult participants with new-onset T1D, long-standing T1D, and healthy controls, comparing factors like age of onset and levels of specific biomarkers.
- Findings showed reduced exocrine function in T1D patients, indicated by lower levels of fecal elastase-1 and serum pancreatic enzymes, with more significant impairment observed in those with long-standing T1D, highlighting the chronic nature of the condition.
Human type 1 diabetes (T1D) is an autoimmune disease associated with major histocompatibility complex polymorphisms, β-cell autoantibodies, and autoreactive T cells. However, there is increasing evidence that innate cells may also play critical roles in T1D. We aimed to monitor peripheral immune cells in early stages of T1D (i.
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