Human papilomaviru-related oropharyngeal squamous cell carcinoma and radiomics: A new era?

Background: The increase of the incidence of human papillomavirus dependent oropharyngeal squamous cell carcinoma is alarming, although we have greatly progressed in the classification and staging of this disease. We now know that human papillomavirus related oropharyngeal squamous cell carcinoma is a sub-type of head and neck squamous cell carcinoma with favourable prognosis and good response to therapy that needs a proper system of classification and staging. Thus, in routine practice it is essential to test patients for the presence of human papillomavirus.

A three-dimensional morphological reconstruction of uterine leiomyoma pseudocapsule vasculature by the Allen-Cahn mathematical model.

Objective: To allow a morphological evaluation of pseudocapsule vasculature of uterine leiomyomas (ULs).

Design: Preliminary prospective study.

Setting: University-affiliated hospitals.