Diabetes insipidus and polydipsia in a patient with Asperger's disorder and an empty sella: a case report.

The paper describes a patient with Asperger disorder, Neurogenic Diabetes Insipidus (NDI) and Primary Empty Sella (ES). His response to vasopressin treatment suggested a concomitant presence of primary polydipsia. This is the first reported case of an autistic spectrum disorder associated with NDI or ES.

[Insulin-dependent diabetes mellitus induced by interferon-alpha].

The efficacy in viral neoplastic illness of IFN alpha therapy is responsible of an increasing use of this drug. Disease like hypothyroidism, thyroiditis, thyreotoxicosis, pernicious anemia, LES, vasculitis, thrombocytopenic purpura and, more recently, diabete mellitus, have been described during IFN alpha therapy. We describe another case of diabetes mellitus induced by IFN alpha.

[A rare case of nonmetastatic paraneoplastic hypercalcemia (humoral hypercalcemia of malignancy) associated with mucinous carcinoma of the stomach].

Humoral Hypercalcemia of Malignancy (HHM) is frequently associated with neoplasms of lung, kidney and ovary. We described a rare case of Humoral Hypercalcemia of Malignancy associated with mucinous gastric carcinoma.

A prospective randomized trial of levothyroxine suppressive therapy for solitary thyroid nodules.

Objective: We examined the effects of L-thyroxine therapy versus placebo over a 12-month period on volume of solitary thyroid nodules.

Design: Prospective randomized clinical trial; placebo and control groups followed for one year in three centres.

Patients: One hundred and one euthyroid patients with single palpable colloid thyroid nodules.

[Hashimoto's thyroiditis presenting as a "hot nodule"].

Hashimoto thyroiditis is clinically the most variable thyroid disease. We describe a case presenting as "hot nodule". This unusual scintigraphic appearance and its possible explanation are discussed.

Hürthle cell hyperplasia and sarcoidosis of the thyroid.

We report of a case of Hürthle cell hyperplasia of the thyroid that was correctly identified preoperatively by fine-needle aspiration cytology but was unexpectedly associated with sarcoid granulomas. To our knowledge, the association has not been previously reported. The rarely described thyroid involvement by sarcoidosis is briefly reviewed.