Publications by authors named "Giacomo Vaudano"

Purpose: Acute ischemic stroke is currently among the main causes of mortality in Western countries. The current guidelines suggest different flowcharts of diagnostic work-up and treatment modalities, including endovascular thrombectomy. Immediately after intra-arterial recanalization, a brain CT scan is usually performed to assess for the presence of peri-procedural complications; in this setting, it is very hard, if possible, to differentiate blood from iodinated contrast material, which is normally present in ischemic tissue because of BBB disruption.

View Article and Find Full Text PDF
Article Synopsis
  • This study explores the effectiveness of a Convolutional Neural Network (CNN) in creating parametric maps from CT perfusion data in patients with acute ischemic stroke.
  • The CNN was trained on 100 pre-processed datasets, and its performance was assessed by comparison with ground truth maps generated by a deconvolution algorithm, showing high accuracy and strong inter-rater agreement.
  • The results indicate that CNN-based perfusion maps can accurately reflect ischemic areas, suggesting promising advancements in machine learning applications for medical imaging and analysis.*
View Article and Find Full Text PDF

Acute necrotising pancreatitis (ANP) is associated with high complication and mortality rates. It is still difficult for the surgeon to choose and schedule the most appropriate treatment. Compared to the past, the current minimally invasive "step-up" approach enables better outcomes in terms of morbidity/mortality, notwithstanding long periods of hospitalisation, and above all ensures better levels of residual pancreatic function.

View Article and Find Full Text PDF

Bilateral simultaneous middle cerebral artery occlusion is a rare condition that may lead to severe neurological disability or death, thus requiring rapid intervention in order to restore vessels patency and brain perfusion. Perfusion-computed tomography is demonstrated to be a fundamental tool for selecting stroke patients candidate to mechanical thrombectomy, but its role for guiding the optimal strategy of endovascular treatment in concomitant multivessel cerebral occlusion has never been reported. We describe a case of bilateral middle cerebral artery occlusion in which perfusion-computed tomography was crucial both for addressing to endovascular procedure and planning the sequence treatment of mechanical thrombectomies.

View Article and Find Full Text PDF

Introduction: An ancillary advantage of bioresorbable scaffolds is the possibility of non-invasive imaging assessment of the treated coronary segment. Cardiac computed tomography angiography (CCTA) studies of resorbable magnesium scaffolds (RMS) are scarce.

Methods: In this collaborative, international study, nine patients who had an RMS implanted underwent CCTA as part of follow-up assessment.

View Article and Find Full Text PDF

Background: Infundibular dilations (IDs) are funnel-shaped enlargements located at the origin of cerebral arteries. Neuroradiologists and neurosurgeons are familiar with IDs of the posterior communicating artery, which are relatively common. Other locations, being unexpected sites of IDs, can pose diagnostic and therapeutic challenges.

View Article and Find Full Text PDF

Purpose: Assess the feasibility, safety and efficacy of TACE with irinotecan loaded micro particles (debiri) for the treatment of locally advanced rectal cancer patients.

Results: We assessed the Edmonton Symptom Assessment System (ESAS). The tool is designed to assess nine common symptoms in cancer patients: pain, tiredness, nausea, depression, anxiety, drowsiness, appetite, wellbeing and shortness of breath.

View Article and Find Full Text PDF

Patients with advanced and incurable colorectal cancer have a very poor prognosis. Curative-intent resection was performed in 70%-90% of cases in reported series of colorectal cancer, sometimes after neoadjuvant chemotherapy and radiotherapy. The remaining 10%-30% of patients are treated with palliative intent, where treatment is aimed at relieving disease-related symptoms and improving quality of life.

View Article and Find Full Text PDF
Article Synopsis
  • Endovascular treatment (ET) is recognized as a safe method for treating acute strokes, but there is ongoing debate about its effectiveness compared to intravenous thrombolysis.
  • The Italian Registry of Endovascular Treatment in Acute Stroke is a national, observational study initiated in 2010 that collects data from various centers to analyze patient outcomes and treatment safety.
  • Over 960 patients were included in the registry from 2008-2012, revealing important insights into treatment methods, safety measures, and demographic characteristics, which can inform future studies on stroke treatments.
View Article and Find Full Text PDF

Acute pyelonephritis (APN) is a frequent disease, but diagnostic approach, evolution into abscesses, and indication to hospitalization are still open problems. We have made a retrospective analysis of APN cases observed in our hospital. We identified 58 patients (pt) and selected 52 of these who presented fever and loin pain at the onset (31 were hospitalized in Nephrology and 21 in other units).

View Article and Find Full Text PDF