Publications by authors named "Giacalone M"

This Letter presents the first measurement of event-by-event fluctuations of the net number (difference between the particle and antiparticle multiplicities) of multistrange hadrons Ξ^{-} and Ξ[over ¯]^{+} and its correlation with the net-kaon number using the data collected by the ALICE Collaboration in pp, p-Pb, and Pb-Pb collisions at a center-of-mass energy per nucleon pair sqrt[s_{NN}]=5.02  TeV. The statistical hadronization model with a correlation over three units of rapidity between hadrons having the same and opposite strangeness content successfully describes the results.

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Brown recluse spider bites may cause symptoms ranging from local cutaneous reactions to systemic visceral loxoscelism. Most bites are self-limiting, but some can lead to necrotic ulcerations with severe complications and soft tissue defects. Necrotizing ulcers are uncommon and have various clinical presentations, so no standard treatment exists.

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In situ immunization (ISI) has emerged as a promising approach to bolster early phases of the cancer immunity cycle through improved T cell priming. One class of ISI agents, oncolytic viruses (OVs), has demonstrated clinical activity, but overall benefit remains limited. Mounting evidence suggests that due to their inherent vulnerability to antiviral effects of type I interferon (IFN), OVs have limited activity in solid tumors expressing stimulator of interferon genes (STING) and/or retinoic acid-inducible gene I (RIG-I).

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Background: The deep inferior epigastric perforator (DIEP) flap is universally considered the gold standard technique for breast reconstruction (BR), though it cannot always be proposed to patients with insufficient donor-site volume. We explore the efficacy of autologous fat transfer (AFT) of the Holm abdomen zone IV in the retropectoral plane during DIEP flap reconstruction (lipo-DIEP flap), to enhance the volume provided by the abdominal donor site in patients with low body mass index (BMI).

Methods: We prospectively enrolled patients with BMI less than 25 kg/m and candidates for lipo-DIEP flap BR (group A) comparing them with a control group (group B) undergoing traditional DIEP flap BR with the same characteristics of the first group (BMI < 25 kg/m).

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Article Synopsis
  • - In situ immunization (ISI) agents are innovative cancer treatments that enhance the body’s immune response to tumors by activating the innate immune system early in the cancer immunity cycle.
  • - This review explores the evolution of ISI agents, their mechanisms, objectives, and compares different therapeutic strategies that have been studied so far.
  • - It also discusses clinical experiences with ISI, addressing both their potential and challenges, while offering a roadmap for future research, particularly in combination therapies and neoadjuvant settings.
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Aim: The aim of this study is to describe circumstances, management and short-term outcomes of neonatal head trauma, and adherence to the Paediatric Emergency Care Applied Research Network (PECARN) head trauma prediction rule for children under 2 years.

Methods: Multicentre retrospective cohort study of neonates (<29 days) with head trauma across 25 emergency departments (ED) from January 2017 to June 2021.

Results: A total of 492 neonates (median age 17 days, range 0-28 days) with non-trivial head trauma were enrolled.

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  • The Letter reports the most accurate measurement so far of the matter-antimatter imbalance during Pb-Pb collisions at a high energy level of 5.02 TeV.
  • It utilizes the Statistical Hadronization framework to determine precise values for the electric charge and baryon chemical potentials, μ_{Q} and μ_{B}.
  • The analysis of antiparticle-to-particle yield ratios shows that the collisions create a system that is generally baryon-free and electrically neutral at midrapidity.
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The ALICE Collaboration reports the measurement of semi-inclusive distributions of charged-particle jets recoiling from a high transverse momentum (high p_{T}) hadron trigger in proton-proton and central Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV. A data-driven statistical method is used to mitigate the large uncorrelated background in central Pb-Pb collisions.

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  • - The study focuses on improving breast reconstruction outcomes using the Latissimus Dorsi (LD) flap technique by developing a formula to estimate flap volume before surgery, potentially reducing the need for follow-up revisions.
  • - Researchers analyzed data from 61 patients, using a water displacement method to measure actual flap volumes and identified body mass index (BMI) and skin paddle width as key predictors in their regression analysis.
  • - The resulting LD-V formula showed strong correlation with actual measurements and is accessible through a web application, offering an easy tool for surgeons to enhance their pre-operative planning and aesthetic results in breast reconstruction.
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  • Histoplasmosis is a fungal infection that mainly affects people with weak immune systems, like those with HIV, especially in certain regions of Europe.
  • A study looked at 78 articles and found 109 patients with this infection, mostly in Italy, France, and Spain, with an average age of 37.
  • Most patients had a serious form of histoplasmosis, and treatments included antifungal medications, but about 24% of the patients sadly passed away. *
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Shiga toxin-producing Escherichia coli-haemolytic uremic syndrome (STEC-HUS) can result in kidney and neurological complications. Early volume-expansion therapy has been shown to improve outcomes, but caution is required to avoid fluid overload. Lung ultrasound scanning (LUS) can be used to detect fluid overload and may be useful in monitoring hydration therapy.

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K^{+}K^{-} pairs may be produced in photonuclear collisions, either from the decays of photoproduced ϕ(1020) mesons or directly as nonresonant K^{+}K^{-} pairs. Measurements of K^{+}K^{-} photoproduction probe the couplings between the ϕ(1020) and charged kaons with photons and nuclear targets. The kaon-proton scattering occurs at energies far above those available elsewhere.

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Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) and Breast Implant-Associated Squamous Cell Carcinoma (BIA-SCC) are emerging neoplastic complications related to breast implants. While BIA-ALCL is often linked to macrotextured implants, current evidence does not suggest an implant-type association for BIA-SCC. Chronic inflammation and genetics have been hypothesized as key pathogenetic players, although for both conditions, the exact mechanisms and specific risks related to breast implants are yet to be established.

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  • - This Letter discusses the measurement of ridge yields from charged hadron angular correlations in proton-proton collisions at a high energy of 13 TeV, specifically within certain pseudorapidity and transverse momentum ranges.
  • - The research extends ridge yield measurements to low charged-particle multiplicity regions, where typically a strong interacting medium is not expected to form during collisions.
  • - Findings indicate that ridge yields in pp collisions are significantly higher than those observed in e^{+}e^{-} collisions, suggesting that processes in e^{+}e^{-} annihilations do not significantly influence long-range correlations in proton-proton interactions.
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  • The ALICE detector measured the cross section for incoherent photonuclear production of J/ψ vector mesons, focusing on the Mandelstam |t| variable, during ultraperipheral collisions of Pb nuclei at a very high energy of 5.02 TeV.
  • The measurement was conducted within a rapidity interval of |y|<0.8 and covers a specific range of Bjorken-x values.
  • Analysis showed that models without quantum fluctuations in the gluon density predicted a much steeper |t|-dependence than observed, but including these fluctuations improved the models' alignment with the data.
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Background: The fat-augmented latissimus dorsi (FALD) flap is an evolution of the traditional latissimus dorsi (LD) flap, which allows to obtain a total autologous breast reconstruction (BR) avoiding the use of breast implants. The aim of this study was to develop a predictive preoperative formula in order to estimate and optimize the amount of fat to be transferred during FALD flap BR, using only anthropometric measurements.

Methods: We conducted a prospective clinical study between September 2020 and April 2023.

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The production of the ψ(2S) charmonium state was measured with ALICE in Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV, in the dimuon decay channel. A significant signal was observed for the first time at LHC energies down to zero transverse momentum, at forward rapidity (2.

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  • Understanding how parton mass and Casimir color factors affect heavy quark emissions is key to studying quantum chromodynamics (QCD).
  • This research presents the first experimental constraint on the charm-quark splitting function, obtained through measurements in proton-proton collisions at 13 TeV.
  • Findings indicate that charm quarks show a steeper splitting function compared to gluons and light quarks, experiencing fewer emissions with a lower likelihood of large-angle emissions.
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Background: Since the first procedure performed in 2005, face transplantation has been debated as viable approach for the treatment of severe craniofacial defects. Despite the benefits provided, the experience in face allotransplantation has brought to light a significant risk of complications, including allograft removal or loss, and mortality. The present study is intended to provide an updated review on complications and major challenges witnessed over 18 years of experience in the field.

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The most precise measurements to date of the _{Λ}^{3}H lifetime τ and Λ separation energy B_{Λ} are obtained using the data sample of Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV collected by ALICE at the LHC. The _{Λ}^{3}H is reconstructed via its charged two-body mesonic decay channel (_{Λ}^{3}H→^{3}He+π^{-} and the charge-conjugate process).

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Background: The fat-augmented latissimus dorsi (FALD) flap combines this pedicled flap with immediate intraoperative fat transfer. Very little is described concerning its inset at the mammary site. Our efforts have concentrated on seeking the best flap orientation and skin-adipose paddle shaping, to improve the aesthetic outcome and to obtain a complete breast reconstruction (BR) in one stage.

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Face transplantation is a viable reconstructive approach for severe craniofacial defects. Despite the evolution witnessed in the field, ethical aspects, clinical and psychosocial implications, public perception, and economic sustainability remain the subject of debate and unanswered questions. Furthermore, poor data reporting and sharing, the absence of standardized metrics for outcome evaluation, and the lack of consensus definitions of success and failure have hampered the development of a "transplantation culture" on a global scale.

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  • * A notable negative correlation between the production of antiprotons and antideuterons was found across various collision centralities.
  • * Comparisons with theoretical models show that while a coalescence calculation explains certain statistical features, it struggles with the specifics of antiproton-antideuteron correlations, whereas thermal-statistical models can align with observations but imply different correlation volumes.
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The transverse-momentum (p_{T}) spectra and coalescence parameters B_{2} of (anti)deuterons are measured in p-p collisions at sqrt[s]=13  TeV for the first time in and out of jets. In this measurement, the direction of the leading particle with the highest p_{T} in the event (p_{T}^{lead}>5  GeV/c) is used as an approximation for the jet axis. The event is consequently divided into three azimuthal regions, and the jet signal is obtained as the difference between the toward region, that contains jet fragmentation products in addition to the underlying event (UE), and the transverse region, which is dominated by the UE.

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