Publications by authors named "Ghulam Murtaza Kamal"
Article Synopsis
- Chronic myeloid leukaemia (CML) is a blood cancer linked to the Philadelphia chromosome and influenced by various genes, including ADGRE2, which could serve as a therapeutic marker.
- The study investigates the impact of non-synonymous SNPs in the ADGRE2 gene on CML's progression using computational tools to assess variant pathogenicity.
- Results showed that the TT genotype of the rs765071211 SNP was significantly associated with CML patients, indicating its potential as a clinical marker for the disease.
Background: Hepatocellular carcinoma (HCC) is a global health concern. Due to late diagnosis and limited therapeutic strategies, HCC based mortality rate is exponentially increasing globally. Genetic predisposition is a non-avoidable intrinsic factor that could alter the genome sequence, ultimately leading to HCC.
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