Challenges of Diagnosing Pseudohypoaldosteronism (PHA) in an Infant.

. Pseudohypoaldosteronism (PHA) is characterized by renal tubular resistance to aldosterone. As a result, the symptoms typically involve hyperkalemia and hyponatremia.

Impaired endothelial function in preadolescent children with type 1 diabetes.

Objective: We evaluated the prevalence of endothelial dysfunction as measured by flow-mediated dilatation (FMD) of the brachial artery and carotid intima-media thickness (c-IMT) in relationship to vascular inflammatory biomarkers in preadolescent children with type 1 diabetes.

Research Design And Methods: We studied 21 type 1 diabetic children (aged 8.3 ± 0.

Factors associated with adherence to continuous subcutaneous insulin infusion in pediatric diabetes.

Background/aims: Continuous subcutaneous insulin infusion (CSII) is a safe and effective alternative to insulin injections in pediatric type 1 diabetes mellitus. CSII can be associated with an increased risk of hypoglycemia and diabetic ketoacidosis (DKA) in some patients. In our Center, patients/guardians are screened for proficiency in diabetes management skills as a prerequisite to initiation of CSII.