Publications by authors named "Ghroubi S"

Multiple sclerosis (MS) can induce cardiac autonomic dysfunction identified by a decreased heart rate variability (HRV) which was linked to oxidative stress, vitamin D deficiency and sleep disturbance. Previous MS studies revealed the antioxidant and anti-inflammatory effects of exogenous melatonin, as well as its benefits on sleep and vitamin D. We aimed to investigate the change in HRV, oxidative stress, systemic inflammation and sleep following melatonin supplementation in MS patients.

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Studying the effects of self-paced concurrent high-intensity interval training and resistance training (HIIT-RT) on respiratory function, cardiopulmonary fitness and fatigue perception in patients with multiple sclerosis (PwMS). Twenty-three PwMS were randomized into a 12-week training group (three times per week) (TG, n = 11) or a control group (CG, n = 12). Lung function (spirometry), aerobic capacity (graded cardiopulmonary-exercise-testing) and perceived fatigue (Fatigue Severity Scale (FSS)) were evaluated pre- and post-intervention.

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Article Synopsis
  • Persons with multiple sclerosis (PwMS) often face issues like sleep disturbances, fatigue, and pain, which can affect their balance and walking, potentially increasing fall risk.
  • This study investigated the long-term effects of chronic melatonin supplementation on PwMS, comparing a melatonin group with a placebo group over 12 weeks.
  • Results showed improvements in dynamic postural stability, walking performance, sleep quality, fatigue perception, and neuropathic pain in the melatonin group, suggesting it could be beneficial for managing symptoms in PwMS.
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Key Clinical Message: Presenting a rare case of flexor carpi radialis atrophy secondary to cervical spondylotic amyotrophy.

Abstract: A 52-year-old man with a history of cervicobrachial neuralgia presented with an advanced atrophy of the right flexor carpi radialis muscle with a groove hollowed out on the anterior surface of the right forearm. The spine MRI showed that this rare atrophy was related to a cervical spondylotic amyotrophy.

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Background: Decreased endogenous melatonin concentrations in people with multiple sclerosis (PwMS) are associated with fatigue and pain that impair postural balance and muscle strength. Melatonin ingestion had analgesic and anti-fatigue effects. However, the acute effect of exogenous melatonin on dynamic postural stability and muscle strength has not been studied yet in PwMS.

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Interval training (IT) has been shown to be a time-effective alternative to traditional training programmes in the management of obesity. Nevertheless, studies comparing the effects of different IT intensities on inflammation, muscle and liver damage, and perceptual responses in people with obesity are relatively scarce. This study aimed to compare the acute effects of two different IT protocols matched by the mean load and duration on biochemical and perceptual responses in sedentary adults with obesity.

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Background And Aims: We investigated, in men with obesity, the efficacy of the combination of two strategies (Ramadan diurnal intermittent fasting 'RDIF' strategy vs RDIF plus concurrent training program 'RDIF-CT' strategy) known for their positive impact on body composition and then we explored the possible impact on metabolic and inflammatory biomarkers.

Methods And Results: Twenty obese men, age: 31.8 ± 7.

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Introduction: We evaluated the effect of intradialytic concurrent (resistance-endurance) training combined with melatonin (MEL) supplementation on functional capacity, muscle strength, postural balance, and quality of life (QoL) in hemodialysis (HD) patients.

Methods: Thirty-three HD patients were randomized into three groups: Exercise (EX)-MEL (n = 11); EX-Placebo (PLA) (n = 11) and Control (C)-PLA (n = 11). Participants included in the EX-MEL and EX-PLA groups were submitted to concurrent training for 12 weeks.

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Patients with stress urinary incontinence (SUI) may be afraid to increase intra-abdominal pressure to avoid incontinence. This could lead to weak expiratory muscles. The aim of this study was to investigate the association between respiratory muscle strength, physical function, and SUI in patients with SUI.

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The electromyographic assessment of the flexor carpi radialis muscle (FCRM) in the context of an upper limb extensors' deficiency helps physicians in differentiating radial nerve damage from C7 radicular impairment. Ultrasound (US)-guided electromyography (EMG) is mandatory to locate this muscle, particularly in the case of muscle atrophy, denervation, and neuromuscular disorders. The aim of this manuscript is to illustrate the anatomical specific features of the FCRM and the technical procedure of FCRM EMG with US guidance.

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Aim: To investigate the gender difference effect on postural balance, functional mobility, and fall risk after performing a fatiguing task in adults with multiple sclerosis (MS).

Methods: Eleven women (30.91 ± 8.

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Article Synopsis
  • The study aimed to evaluate the safety and effectiveness of nocturnal melatonin (6 mg) consumption on balance, mobility, and fall risk in adults with relapsing-remitting multiple sclerosis (MS).
  • Fourteen participants were assessed through various tests measuring balance, mobility, cognitive performance, and sleep quality before and after taking melatonin or a placebo.
  • Results indicated that melatonin improved postural balance, decreased mobility test durations, and enhanced cognitive function and sleep quality compared to the placebo group.
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Objectives: Studies have shown that there is co-activation between abdominal and pelvic floor muscles (PFM) in physiological conditions. This study aimed to assess pelvic floor and isokinetic trunk flexors function in non-active incontinent women, and to investigate the association between the strength of these muscle groups and the severity of stress urinary incontinence (SUI).

Methods: A cross-sectional study was carried out.

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Background: Intense physical exercise leads to inflammation, oxidative stress and muscle damage, and these responses are of greater magnitude in people with obesity. Melatonin (MLT) is considered an endogenous antioxidant which may have beneficial effects against inflammation, oxidative stress and promote tissue repair after exercise. The aim of this study was to examine the effect of MLT on inflammatory parameters, oxidative stress and muscle damage in people with overweight/obesity after a high-intensity interval exercise (HIIE).

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The extensor indicis proprius muscle (EIPM) is considered a key muscle in the assessment of the level of the neurologic lesion causing any motor or sensory medio-cubital impairment of the hand. The aim of this study is to illustrate the anatomical peculiarities of the EIPM, the ultrasound (US) anatomy of the inferoposterior part of the forearm, and the technique of US-guided electromyography (EMG) of the EIPM. The US-guided EMG of the EIPM is technically easy and safe for young practitioners, provided there is a good knowledge of US anatomy of the inferoposterior part of the forearm.

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The posterior tibial muscle (PTM) is a key muscle in diagnosing the level of the neurologic lesion that causes steppage gate that is a paralysis of nervous origin of the muscles ensuring the foot dorsiflexion. The aim of this manuscript is to illustrate the anatomical peculiarities of the PTM, the ultrasound (US) anatomy of the infero-posterior part of the leg, and the technique of US-guided electro-neuro-myography (ENMG) of the PTM, which is considered a key muscle in the diagnosis of the neurological lesion causing steppage gate. The US-guided ENMG of the PTM is technically easy and safe for young practitioners provided there is a good knowledge of US anatomy of the infero-posterior part of the leg.

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Introduction: this study aimed to evaluate the effectiveness of botulinum toxin A (BoNT-A) injection in hemiparetic patients with chronic spasticity in the upper limb resulting from stroke or traumatic brain injury.

Methods: we conducted a retrospective study including 45 patients seen, in our department of Physical Medicine and Rehabilitation, between January 2014 and December 2016. All patients received an injection of BoNT-A (Dysport, 100 U/ml).

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: To translate and validate an Arabic (Tunisian) version of the Urogenital Distress Inventory short form (UDI-6) and Incontinence Impact Questionnaire short form (IIQ-7), which can be used reliably in daily practice and clinical research for Tunisian and Arabic populations. : This cross-sectional study was conducted from January to June 2018. The UDI-6 assesses the presence of urinary incontinence (UI) and the degree of impairment that it causes, whilst the IIQ-7 evaluates women's life quality with lower urinary tract symptoms.

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: To translate and validate linguistically an Arabic version of the Intermittent Catheterisation Difficulty Questionnaire (ICDQ) adapted to the Tunisian population. : An Arabic translation and cultural adaptation of the ICDQ was obtained via the reverse translation method after two sets of comprehension tests within two groups of 10 patients. Psychometric validation included testing the questionnaire on a group of 30 patients.

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Objective: To translate and linguistically validate in classical Arabic; the French version of the neurogenic bowel dysfunction (NBD).

Patients And Methods: Arabic translation of the NBD score was obtained by the "forward translation/backword translation" method. Patients with multiple sclerosis (MS) and spinal cord injury were included.

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Aims: Our objective was to evaluate the specific effect of isokinetic muscle strength enhancement in the rehabilitation of obese subjects by comparing two groups (isokinetic muscle exercising associated with aerobic exercising or only aerobic exercising).

Patients And Methods: This was a randomized, prospective study from January 2008 to December 2009 involving 40 obese patients randomized into two groups. The first group G1 (n=20) followed a program of aerobic training and isokinetic exercising of the extensor and flexor muscles of lower limbs and spine.

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Background: The prevalence of children obesity is rising alarmingly in both developed and developing countries. Developing effective exercise programs is a strategy for decreasing this prevalence and limiting obesity-associated long-term comorbidities.

Objectives: To determine whether a 16-week training program; in addition to the school physical education and without dietary intervention; could have beneficial effects on body composition and aerobic capacity of obese children.

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Background Context: Concerns have been raised about the effect of backpack carrying on adolescent balance. For adolescent idiopathic scoliosis (AIS) subjects, the effect of backpack carrying method on their balance has not been determined. Our aim is to examine the effects of backpack load and carrying method on AIS subjects' balance.

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Objective: Study the effect of muscle strength training on muscle strength, maximal oxygen uptake (VO2max), hemodynamic and anthropometric parameters as well as quality of life after coronary artery bypass grafting (CABG).

Methods: After CABG surgery, 32 patients were randomized into two groups. The first group was to perform aerobic-type training with a cycle ergometer (AT=16).

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