High frequency of anti-Saccharomyces cerevisiae antibodies in chronic hepatitis C.

Background And Study Aim: Chronic hepatitis C (CHC) is a liver disease caused by the hepatitis C virus. Anti-Saccharomyces cerevisiae (S. cerevisiae) antibodies (ASCA) are frequently reported in autoimmune diseases but rarely in viral infections.

Autoantibodies Serum Level and 10-Year Risk of Fractures Evaluated by FRAX Tool in Rheumatoid Arthritis Patients.

Purpose: FRAX is a tool used for evaluation of risk of fracture in RA and non-RA patients and to identify those eligible for intervention. One of the limitations of FRAX in RA settings is that it does not consider factors known to contribute to osteoporosis such as autoantibodies. This study analysed the association of anti-mutated citrullinated vimentin antibody (anti-MCV), anti-cyclic citrullinated peptide antibody (anti-CCP), IgM rheumatoid factor (RF), IgA RF with 10-year risk of major osteoporosis and hip fracture.

Serological screening for celiac disease, by endomysial antibodies, in patients with rheumatoid arthritis.

Celiac disease (CD) and rheumathoid arthritis (RA) are both multi-factorial chronic inflammatory auto-immune diseases. In this retrospective study, we determined the frequency of CD in patients with RA using IgA anti-endomysial antibodies (EmA) and tried to explain this association. Indirect immunofluorescence on human umbilical cord was used to detect EmA in 215 patients with seropositive RA collected over a 4-year-period.

IgA is the predominant isotype of anti-β2 glycoprotein I in patients with COVID-19.

Objective: The aim of this research was to determine the frequency of antiphospholipid antibodies (aPL) in patients with COVID-19.

Methods: The frequency and titers of anticardiolipin antibodies (aCL) and anti-β2 glycoprotein I antibodies (aβ2GPI) were determined in sera of adult patients hospitalized with COVID-19. Immunoglobulin (Ig)G, IgA, IgM aCL, and aβ2GPI were measured using enzyme-linked immunosorbent assay.

Frequency of serological markers of rheumatoid arthritis in patients with Hashimoto's thyroiditis.

Background: Hashimoto's thyroiditis (HT) is an autoimmune disease that is frequently associated with other autoimmune conditions.

Objective: To perform serological screening for rheumatoid arthritis (RA) in patients with HT.

Methods: Our study included 88 consecutive serum specimens of patients with confirmed HT and 88 sex- and age-matched healthy subjects.

Anti-cardiolipin and anti-beta 2 glycoprotein I antibodies in patients with type 1 diabetes.

To determine the frequency of anti-phospholipid antibodies (aPL) in particular anti-cardiolipin antibodies (aCL) and anti-beta 2 glycoprotein I antibodies (aβ2GPI) in Tunisian patients with type 1 diabetes. One hundred and two patients with type 1 diabetes (34 children, 68 adults) were studied. As control groups, we used sera of 156 adults and 65 children without type 1 diabetes.

Frequency of antithyroid antibodies in patients with primary biliary cholangitis.

Objective: Primary biliary cholangitis (PBC) is an autoimmune disease of liver that may be associated with other conditions, including autoimmune thyroid diseases. We aimed to investigate the frequency of anti-thyroperoxidase antibodies (TPO-Ab), antithyroglobulin antibodies (TG-Ab), and anti-thyrotropin receptor antibodies (TSHR-Ab) in Tunisian patients with PBC.

Methods: Sera of 80 patients with PBC were collected over a 9-year period.

Serological markers of rheumatoid arthritis in patients with primary biliary cholangitis and the vice versa: A Tunisian study.

Background: Primary biliary cholangitis (PBC) is an autoimmune disease of the liver characterized by destructive lymphocytic cholangitis and anti-mitochondrial antibodies (AMA). Anti-gp210 and anti-Sp100, are used for the diagnosis of PBC in AMA-negative PBC patients. Patients with PBC have a propensity to have an extrahepatic manifestation which is especially autoimmune.

Positive myositis-specific autoantibodies during COVID-19: a case report.

Viral infection is known to be a trigger of autoimmune diseases. Numerous cases of coronavirus disease 2019 (COVID-19) with autoimmune manifestations have been reported and several authors have highlighted the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and autoimmune diseases. Autoimmune myopathies being one of these manifestations.

Anticardiolipin and anti-beta 2-glycoprotein I antibodies in patients with unexplained articular manifestations.

Objective: To determine the frequency of antiphospholipid antibodies (aPL) in patients with unexplained articular manifestations.

Material And Methods: Three hundred thirteen patients suffering from arthritis or arthralgia without evident cause and 266 healthy blood donors (HBD) were included in the study. Anticardiolipin antibodies (aCL) and anti-beta 2-glycoprotein I antibodies (aβ2GPI) were measured by ELISA.

Antiphospholipid antibodies in autoimmune thyroid diseases.

Background: Antiphospholipid (aPL) antibodies have been reported in several autoimmune diseases. The aim of this study was to evaluate the frequency of aPL (anti-cardiolipin antibodies (aCL) and anti-β2 glycoprotein I antibodies (aβ2GPI)) in patients with autoimmune thyroid diseases (AITD).

Methods: One hundred and ninety-five patients with AITD (139 Hashimoto's thyroiditis (HT) patients and 56 Graves' disease (GD) patients) and 90 healthy blood donors (HBD) were studied.

Anti-Saccharomyces cerevisiae Antibodies in Rheumatoid Arthritis.

Objective: This study was conducted to evaluate the frequency of anti-Saccharomyces cerevisiae antibodies (ASCA) in patients with rheumatoid arthritis (RA).

Methods: Eighty-three RA patients with positive anti-cyclic citrullinated antibodies (anti-CCP) and 160 healthy blood donors were included in this study. ASCA IgG and IgA were assessed with enzyme-linked immunosorbent assay.

Frequency of serological markers of rheumatoid arthritis in patients with IgA anti-β2 glycoprotein I antibodies.

Aim: To determine the frequency of serological markers of RA in patients with anti-β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype.

Material And Methods: A retrospective study was conducted on 67 patients with aβ2GPI-IgA. Ninety healthy blood donors (HBD) were used as a control group.

A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis.

Objectives: Little is known about genes predisposing to systemic bone loss (SBL) in rheumatoid arthritis (RA). Therefore, we examined the association between SBL and variants of genes playing a critical role in both immune response and bone homeostasis among patients with RA.

Methods: IRAK-1 rs3027898, IRAK-2 rs3844283, IRAK-2 rs708035, IFIH1 rs1990760, CD40 rs48104850, TNFAIP3 rs2230926, and miR146-a rs2910164 were genotyped in 176 adult RA patients.

Frequency of serological markers of rheumatoid arthritis in adult patients with active celiac disease.

Background: Celiac disease (CD) and rheumatoid arthritis (RA) are multisystem autoimmune diseases affecting 1% of general populationa. Both diseases share genetic and immunological features.

Aim: In this retrospective study, we aim to determine the frequency of auto-antibodies of RA in adult patients with CD.

Optimized Electrode/Electrolyte Interface of MWCNT/SnO Composite through Gas-Solid Fluorination.

The benefit of enriching solid-electrolyte interface with fluorine atoms through the use of fluorinated additives into the electrolyte composition has recently gained popularity for anode materials used in secondary lithium-ion batteries. Another strategy is to provide these fluorine atoms via surface fluorination of the electrode material, particularly for multiwalled carbon nanotube (MWCNT)/SnO-based composites where fluorination must act selectively on SnO. Our study presents two methods of surface fluorination applied on MWCNT/SnO, one using F(g) and the other XeF(s).

Three zinc(II) and cadmium(II) complexes containing 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole and polynitrile ligands: synthesis, molecular and supramolecular structures, and photoluminescence properties.

Three photoluminescent complexes containing either Zn or Cd have been synthesized and their structures determined. Bis[4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole-κN,N]bis(dicyanamido-κN)zinc(II), [Zn(CHN)(CN)], (I), bis[4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole-κN,N]bis(dicyanamido-κN)cadmium(II), [Cd(CHN)(CN)], (II), and bis[4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole-κN,N]bis(tricyanomethanido-κN)cadmium(II), [Cd(CHN)(CN)], (III), all crystallize in the space group P-1, with the metal centres lying on centres of inversion, but neither analogues (I) and (II) nor Cd complexes (II) and (III) are isomorphous. A combination of N-H.

Screening for celiac disease, by endomysial antibodies, in patients with unexplained hypertransaminasaemia.

Objective: To do a serological screening for celiac disease in patients with unexplained liver cytolysis.

Materials And Methods: Fifty-six patients with liver cytolysis without known aetiology were studied. Endomysial antibodies were determined by indirect immunofluorescence on human umbilical cord.

High frequency of antiphospholipid antibodies in primary biliary cirrhosis.

Aim: To evaluate, retrospectively, the frequency of autoantibodies of antiphospholipid syndrome (APLS) in Tunisian patients with primary biliary cirrhosis (PBC).

Patients And Methods: We analyzed 80 PBC sera and 80 sera from blood donors. ELISA was used to determine the frequency of antibodies against cardiolipin (aCL IgG, IgA, and IgM) and beta 2 glycoprotein I (aβ2GPI IgG, IgA, and IgM).

Macrocyclic arylopeptoids--a novel type of cyclic N-alkylated aromatic oligoamides forming nanotubular assemblies.

The head-to-tail conversion of linear arylopeptoids (oligomeric N-substituted aminomethyl benzamides) into the derived novel macrocycles has enabled the first X-ray structures of arylopeptoid constructs and the identification of well-defined architectures in solution.

Poly[[chlorido(1,10-phenanthroline-κ2N,N')copper(II)]-μ3-1,1,3,3-tetracyano-2-ethoxypropenido-κ3N:N':N'']: coordination polymer sheets linked into bilayers by hydrogen bonds.

In the title compound, [Cu(C9H5N4O)Cl(C12H8N2)]n or [Cu(tcnoet)Cl(phen)]n, where phen is 1,10-phenanthroline and tcnoet is 1,1,3,3-tetracyano-2-ethoxypropenide, the axially elongated (4 + 2) coordination polyhedron around the Cu(II) centre contains N atoms from three different tcnoet ligands. The resulting coordination polymer takes the form of sheets which are linked in pairs by a single C-H..

Screening for celiac disease, by endomysial antibodies, in patients with unexplained articular manifestations.

Celiac disease (CD) is an autoimmune systemic disease characterized by not only gastrointestinal but also extraintestinal manifestations. The aim of our study was to do a serological screening for CD, by IgA endomysial antibodies (EmA), in patients with unexplained articular manifestations. Two hundred and eleven patients suffering from arthritis or arthralgia without evident cause were studied.

Scleromyxedema: a case report and review of the literature.

Scleromyxedema (SM) is a sclerotic variant of lichen or papular mucinosis in which lichenoid papules and scleroderma-like features are both present. It is a rare deposition disorder characterized by generalized papular and sclerodermoid eruptions, mucin deposition, increased fibroblast proliferation, fibrosis, and monoclonal gammopathy (also known as paraproteinemia) mainly of the immunoglobulin G-lambda type in the absence of thyroid disease. It usually affects middle-aged adults and shows no gender or racial predilection.