Publications by authors named "Ghole V"

Several treatment technologies are available for the treatment of palm oil mill wastes. Vermicomposting is widely recognized as efficient, eco-friendly methods for converting organic waste materials to valuable products. This study evaluates the effect of different vermicompost extracts obtained from palm oil mill effluent (POME) and palm-pressed fiber (PPF) mixtures on the germination, growth, relative toxicity, and photosynthetic pigments of mung beans (Vigna radiata) plant.

View Article and Find Full Text PDF

Fly ash is toxic and its escalating use as a soil amendment and disposal by dumping into environment is receiving alarming attention due to its impact on environment. Proteomics technology is being used for environmental studies since proteins respond rapidly when an organism is exposed to a toxicant, and hence soil engineers such as earthworms are used as model organisms to assess the toxic effects of soil toxicants. This study adopted proteomics technology and profiled proteome of earthworm Dichogaster curgensis that was exposed to fly ash, with main aim to elucidate fly ash effects on cellular and metabolic pathways.

View Article and Find Full Text PDF

Earthworms are globally accepted as a model organism in terrestrial ecotoxicology for assessment of environmental pollution. This study evaluated and compared effects of fly ash polluted soils collected from two geographically different thermal power plants on biomarker responses in the earthworm, Dichogaster curgensis. To evaluate relationship between distance sampling and biomarker responses in the earthworm D.

View Article and Find Full Text PDF

Present methods for the disposal of old and rejected ammunition carry high risk and are not environment-friendly. Various processes such as wet air oxidation, molten salt oxidation, hydro thermal oxidation, incineration, electrochemical reduction, biodegradation and other methods have limited use for decontamination and are not suitable for disposal of large quantities of explosives. Thus there is dire need to develop alternate method for safe disposal of rejected explosives which will be eco-friendly.

View Article and Find Full Text PDF

Semi-arid Karha basin from Deccan Volcanic Province, India was investigated for inter-annual variability of urolithiasis epidemic. The number of reported urolith patient, weather station data and groundwater quality results was used to assess impact of geoenvironment on urolithiasis. Data of 7081 urolith patient were processed for epidemiological study.

View Article and Find Full Text PDF

Breast cancer, especially ER positive/HER2/neu negative IDC, is the predominant subtype of invasive ductal carcinoma. Although proteomic approaches have been used towards biomarker discovery in clinical breast cancer, ER positive/HER2/neu negative IDC is the least studied subtype. To discover biomarkers, as well as to understand the molecular events associated with disease progression of estrogen receptor positive/HER2/neu negative subtype of invasive ductal carcinoma, differential protein expression profiling was performed by using LC-MS(E) (MS at elevated energy).

View Article and Find Full Text PDF

Fly ash is receiving alarming attention due to its hazardous nature, widespread usage, and the manner of disposal; leading to environmental deterioration. We carried out bio-monitoring and risk assessment of fly ash in earthworms as a model system. Dichogaster curgensis were allowed to grow in presence or absence of fly ash (0-40%, w/w) for 1, 7, and 14 d.

View Article and Find Full Text PDF

Cancer is associated with increased glycolysis and carbonyl stress. In view of this, AGE modified proteins were identified from clinical breast cancer tissue using 2DE-immunoblot and mass-spectrometry. These proteins were identified to be serotransferrin, fibrinogen gamma chain, glycerol-3-phosphate dehydrogenase, lactate dehydrogenase, annexin II, prohibitin and peroxiredoxin 6, which have established role in cancer.

View Article and Find Full Text PDF

The quality of water recourses is degrading due to improper wastewater management. The aim of this study is to examine the potential of bio-rack system for treatment of domestic wastewater in the presence of high total dissolved solids (TDS) and heavy metal salts. The bio-rack is a modified wetland system incorporated with the advantages of phytoremediation and attached growth microbial process.

View Article and Find Full Text PDF

Monoethylene glycol (MEG) undergoes various stages during metabolic degradation pathways from acetaldehydes to acetic acid before converting to carbon dioxide and water in a degradation process. Sequential degradation of MEG through biological route obsesses higher retention time. Ozone is considered as an effective oxidant for MEG degradation but involves higher operating cost.

View Article and Find Full Text PDF

Safe, economic and effective treatment of domestic wastewater is the biggest challenge the world experienced in modern times. Phytoremediation studies were undertaken in a laboratory scale using shallow pond water hyacinth (Echhornia crassipes) system and analytical data was collected before and after treatment. The studies also include microbial flora present in the system by isolating and identifying the microorganisms.

View Article and Find Full Text PDF

VMNS2e is a novel biphenyl compound, which in previous studies had showed most favourable interactions with the active site of protein tyrosine phosphatase 1B (PTP1B). The effect of acute and chronic treatment of VMNS2e (30mg/kg) was investigated in ob/ob mice. Plasma glucose was measured after acute administration of VMNS2e (30mg/kg) in both lean and ob/ob mice.

View Article and Find Full Text PDF

Aim: To study the effect of a new biphenyl synthetic compound showing interactions with the active site of protein tyrosine phosphatase 1B by docking and molecular dynamics, VMNS2e in streptozotocin-induced diabetic nephropathy in rats with various renal function parameters and renal ultrastructure.

Methods: Streptozotocin (55 mg/kg)-induced diabetic rats were orally treated once daily with VMNS2e (30, 60, and 120 mg/kg) for 8 weeks. The body weight and blood glucose levels of the rats were recorded during the study period.

View Article and Find Full Text PDF

The aim of the present study was to devise and validate an appropriate treatment process for disposal of hazardous barium and cyanide waste into a landfill at a Common Hazardous Waste Treatment Storage Disposal Facility (CHWTSDF). The waste was generated during the process of hardening of steel components and contains cyanide (reactive) and barium (toxic) as major contaminants. In the present study chemical fixation of the contaminants was carried out.

View Article and Find Full Text PDF

The aim of the present study was to evaluate the acute toxicity of anaerobically treated distillery effluent and oxidized effluent on freshwater fish, Cyprinus carpio. The untreated distillery effluent (Sample A) was treated with up-flow anaerobic sludge blanket (UASB) reactor (Sample B) and followed by an oxidizer system (Sample C and D) under optimized conditions. The comparative acute toxicity of Sample A and treated effluents (Sample B, C and D) was studied using Cyprinus carpio (common carp) as a model fish for various exposure times (24 to 96 h) after suitable dilutions.

View Article and Find Full Text PDF

Background: Air pollutants of iron- and steel-making operations have historically been an environmental and health hazard. These pollutants include gaseous substances such as sulfur oxide, nitrogen dioxide, and carbon monoxide. The Iran National Steel Industrial Group beam rolling mills factory has two production lines viz.

View Article and Find Full Text PDF

Plasmacytomas occurring in the gastrointestinal tract are extremely rare. We report one such case of pancreatic and jejunal plasmacytoma in a single patient with known multiple myeloma with emphasis on computed tomographic (CT) findings.

View Article and Find Full Text PDF

Various long-term complications have been reported with inferior vena cava filters. In this report, the authors describe unusual complications associated with a G2 filter in a patient with aortic lumen and vertebral body penetration.

View Article and Find Full Text PDF

Wastewater containing monoethylene glycol (MEG) was investigated for biodegradation on a continuous bench scale bioreactor applying an activated sludge process. The bacterial consortia were prepared using three isolated bacterial strains and process conditions, viz. HRT, biomass concentration and air requirements were optimized to achieve efficient biodegradation.

View Article and Find Full Text PDF

Possibility of perchlorate reduction by microbes raises hope for an eco-friendly mode of degradation of this toxic rocket fuel. This study reports 3 isolates (A1, A2 and A3) capable of molybdenum-independent degradation of perchlorate under aerobic conditions. The rate of degradation was the highest when perchlorate concentration was 17 mM, and then 3.

View Article and Find Full Text PDF

Extramedullary hematopoiesis is manifested by several clinical hematological disorders. Its localization to presacral space as mass is extremely rare. We report one such case in a patient with hereditary spherocytosis.

View Article and Find Full Text PDF

A field experiment was conducted to evaluate the effect of different nutrients on canola (Brassica napus L.) growth parameters, nutrient uptake and ultimately on seed yield. For this purpose a split plot experimental design, with 10 treatments in 4 replications was carried out in 2004-2005, in silt-clay soil at Baiecola Agricultural Research Station, Mazandaran Iran.

View Article and Find Full Text PDF

Workers of iron and steel factories are exposed to a wide range of pollutants depending on the particular process, the materials involved, the effectiveness of monitoring and the control measures. Adverse effects are determined by the physical state and propensities of the pollutant involved, the intensity and duration of the exposure, the extent of pollutant accumulation in the body and the sensitivity of the individual to its effects. The main aim of this study is to assess the levels of the indoor respirable particulate matter (RPM) and to compare the health condition of exposed workers, with nonexposed employees group.

View Article and Find Full Text PDF

A large amount of energetic materials including propellants, high explosives, pyrotechnics are subjected to disposal either due to expiry of their useful life or rejection in the manufacturing process. The environmental regulations do not allow the hazardous materials for open burning / detonation in view of the health hazard involved in these operations. The present paper describes the hazard potential of energetic materials and associated hazardous chemicals.

View Article and Find Full Text PDF