Effects of maternal diazinon exposure on frontal cerebral cortical development in mouse embryo.

Background: Diazinon including organophosphate (OP) that is widely used in agriculture and animal husbandry industry and the risk of human infection with the toxin and their toxicity.

Methods: Pregnant balb/c mice (30-35 g) were randomly divided into five groups of five: the control group (no intervention), two sham groups (emulsifier 0.52, and 5.

Modified PLGA nanofibers as a nerve regenerator with Schwann cells.

Polylactide-co-glycolide acid (PLGA) is known as a biodegradable and biocompatible polymer. This polymer has been highly used in tissue engineering. In this study, the biological behavior of Schwann cells (Rat) was investigated in co-culture with L lysine/gelatine coated PLGA nano-fiber.

Study of transected sciatic nerve repair by biodegradable membrane and betamethasone in adult albino wistar rats.

Aim: One of the major injuries of the nervous system is that of peripheral nerves. Although peripheral nerves show some capacity of regeneration after injury, the extent of regeneration is not remarkable. The present study aimed to evaluate the regeneration of the transected sciatic nerve by membrane and betamethasone in rats.

A model portraying experimental loss of hair cell: the use of distortion product otoacoustic emission in the assessment of rat's ear.

The use of rats in research academies to study deafness is widespread, meanwhile medicinal methods to eliminate hair cells is also increasing. Thus, aminoglycosides and loop diuretics have grasped more attention. This study aimed at establishing an animal model in which a rapid distortion of the hair cell of cochlea administering amikacin and furosemide and using distortion product otoacoustic emission (DPOAE) the functioning of rat's ear would be assessed.

In vitro differentiation of bone marrow stromal cells into oligodendrocyte-like cells using triiodothyronine as inducer.

An in vitro technique was devised to induced autologous adult stem cells into oligodendrocyte-like cells. In this study, a protocol was developed for the induction of bone marrow stromal cells (BMSCs) into oligodendrocyte-like cells. BMSCs were incubated in one of these three pre-inducers: dimethyl sulfoxide (DMSO), β-mercaptoethanol (βME) or biotylated hydroxyanisol (BHA), each followed by retinoic acid (RA) treatment.

Prophylactic ophthalmic bethametazone for sulfur mustard-induced ocular injury.

Background: The present study sought to evaluate the prophylactic effect of bethametazone on sulfur mustard (SM)-induced ocular morphometric damage in the rabbit eye.

Methods: Twenty five healthy New Zealand white rabbits were divided into 4 groups of normal (not exposed to SM or solution), solution (exposed to solution), SM (exposed to SM), and prophylactic bethametazone (received eye solution of bethametazone then exposed to SM solution; then treated for 2 weeks). On the day 14 after exposure, five-micron sections were stained with haematoxylin and eosin for light microscopy evaluation.

Effects of maternal oral administration of morphine sulfate on developing rat fetal cerebrum: a morphometrical evaluation.

Intrauterine morphine exposure is a risk factor for neurological and behavioral deficit in children, although the precise underlying biological correlate for this is unclear. Female pregnant rats were orally treated with 0.1 mg/ml of morphine solution on the 21st day of gestation.

Effects of maternal oral morphine consumption on neural tube development in Wistar rats.

Opiate abuse during pregnancy may result in abnormal nervous system function. In order to evaluate the effects of morphine on the development of the nervous system, the present study focused on the effects of maternal morphine consumption on neural tube development in Wistar rats. Female Wistar rats (250-300 g) were crossed with male rats and coupling time was recorded (embryonic day 0-E0).