Publications by authors named "Gholam Hossein Naderi"
Primary hyperoxaluria Type-1 (PH-1) is caused by a deficiency of alanine-glyoxylate aminotransferase manifesting as urolithiasis, nephrocalcinosis, and end-stage renal disease (ESRD). Among treatment options, best outcomes have been achieved by sequential liver-kidney transplantation (Seq-LKT). Herein, we report a patient with PH-1 and ESRD who underwent Seq-LKT in Iran.
View Article and Find Full Text PDFPurpose: The aim of this study was to compare the penile cuff test (PCT) and standard pressure-flow study (PFS) in patients with bladder outlet obstruction.
Materials And Methods: A total of 58 male patients with moderate to severe lower urinary tract symptoms (LUTS) were selected. Seven patients were excluded; thus, 51 patients were finally enrolled.
Introduction: Development of delayed graft function is more prevalent in patients receiving a kidney allograft from brain-dead than living donors. This study aimed to evaluate the association between urine neutrophil gelatinase-associated lipocalin (NGAL) levels in brain-dead donors and subsequent allograft function.
Materials And Methods: Urine NGAL concentration was measured in urine samples obtained from 24 brain-dead kidney allograft donors before organ retrieval.
Varicocele, the most common cause of male infertility, is defined as abnormal dilation of the pampiniform plexus. Although different mechanisms have been proposed to explain the pathophysiology of infertility caused by varicocele, it is still open to debate. Previous studies have demonstrated the effect of insulin-like growth factor-I (IGF-I) on semen quality in animals and humans, but there are no studies on the probable role of seminal IGF-I in the pathophysiology of infertility among patients with clinical varicocele.
View Article and Find Full Text PDFArticle Synopsis
- PH type 2 results from low GRHPR enzyme activity, which can lead to end-stage renal disease (ESRD) and systemic oxalosis.
- An Iranian pediatric patient diagnosed at age five underwent isolated kidney transplantation at nine due to early ESRD caused by recurrent calcium oxalate stones and elevated oxalate levels.
- Post-transplant complications included increased serum creatinine and renal tubular obstruction, ultimately leading to graft nephrectomy, suggesting that a combined liver-kidney transplant might be a better option for similar patients with PH2.
Introduction: As an immunosuppressive treatment, cyclosporine carries a significant risk of nephrotoxicity. In this study, we assessed the safety and efficacy of sirolimus conversion in our kidney transplant recipients.
Materials And Methods: Sirolimus conversion in 99 kidney transplant recipients was evaluated.
Introduction: The conventional treatment of acute kidney allograft rejection consists of high-dose corticosteroids and polyclonal antibodies. We report our experience of tacrolimus rescue therapy in patients with acute rejections refractory to corticosteroids and polyclonal antibodies.
Materials And Methods: A total of 34 patients with a mean age of 42.
Introduction: Our aim was to evaluate the relationship between lower urinary tract symptoms (LUTS), age, and sexual dysfunction in the Iranian men aged 50 to 80 years.
Materials And Methods: A total of 357 men aged 50 to 80 years presenting at the urological clinic were enrolled in this study. The International Prostatic Symptom Score (IPSS) and the International Index of Erectile Function (IIEF) questionnaires were used to assess the LUTS and sexual function, respectively.