Therapeutic response to ramucirumab + folfiri in patients with metastatic gastric cancer.

Background: Gastric tumors are important gastrointestinal malignancies, and the prediction of therapeutic responses and related factors are important to improve the prognosis. Hence the aim of this study was to determine the therapeutic response to ramucirumab + folfiri in patients with metastatic gastric cancer.

Methods And Materials: In this prospective cohort, 13 consecutive patients with metastatic gastric cancer attending Taleghani Hospital that underwent ramucirumab + folfiri therapy were enrolled, and the therapeutic response among them was determined.

Epidemiologic and Pathologic Study of Pancreatic Cancer in Hamadan, Iran (2008 to 2018).

Purpose: Pancreatic cancer is the seventh leading cause of cancer death in cases. The study was conducted to determine the epidemiologic and pathologic of pancreatic cancer METHODS: A case series study was conducted retrospectively at Beheshti Hospital in Hamadan, Iran. A total of 409 cases that had been diagnosed with pancreatic cancer from 2008 to 2018 were reviewed.

The effects of IL-8, IL- 6, and IL-1 on the risk of celiac disease: a Bayesian regression analysis.

Aim: The present study aimed to evaluate the association between serum levels of interleukin IL-1, IL-6, IL-8 genes as well as interferon (IFN)-γ and the risk of celiac disease (CD).

Background: The role of serum cytokine levels in the pathophysiology of CD is still an open field to be explored.

Methods: This case-control study was performed on 110 patients with CD and 46 healthy controls referring to Taleghani Hospital, Tehran, Iran.

Detection of B. fragilis group and diversity of bft enterotoxin and antibiotic resistance markers cepA, cfiA and nim among intestinal Bacteroides fragilis strains in patients with inflammatory bowel disease.

We compared frequency of the members of B. fragilis group in 100 and 20 colon biopsy specimens of inflammatory bowel disease (IBD) and non-IBD patients. Agar dilution and PCR were orderly used to detect minimal inhibitory concentration of ampicillin, imipenem, and metronidazole, and carriage of related resistance genes cepA, cfi, and nim.

Correlation between the Intensity of Colonization and Severity of Gastritis.

Background: The most common cause of chronic gastritis is infection with . Identifying the relationship between intensities of colonization and activity of gastritis helps the clinician in more effective treatment and posttreatment follow-ups.

Methods: In this cross-sectional study, endoscopic gastric biopsy samples of 544 patients who complained symptoms of dyspepsia for more than three months referring to the laboratory were studied.

Psychological features in patients with and without irritable bowel syndrome: A case-control study using Symptom Checklist-90-Revised.

Context: Recent studies have demonstrated that a high proportion of irritable bowel syndrome (IBS) patients shows an association with psychological factors. A few studies were conducted on the investigation of psychological features of IBS patients in Iran.

Aims: We aimed to evaluate the relationship of psychological distress with IBS in outpatient subjects.

Anxiety and depression in a sample of Iranian patients with irritable bowel syndrome.

Objective: Previous studies have shown that up to 50% to 70% of patients with irritable bowel syndrome (IBS) who seek treatment have psychiatric comorbidity. The aim of this study was to report the history of anxiety and depression in IBS patients.

Methods: The study, designed as a cross-sectional, was performed in a consecutive sample of individuals diagnosed with IBS in the Gastroenterology Clinic of Taleghani Hospital, Tehran province, Iran from October 2010 to October 2011.

Cholangiocarcinoma: an-eight-year experience in a tertiary-center in Iran.

Background And Aim: Cholangiocarcinoma (CCA) is an uncommon malignancy of the bile duct, occurring in nearly 2 out of 100,000 people. It is a type of adenocarcinoma that originates in the mucous glands of the epithelium, or surface layers of the bile ducts. The aim of this study was to evaluate the clinical features, diagnostic results and factors associated with survival, morbidity and mortalityof cholangiocarcinoma cases in Iranian patients.

The efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of H.pylori: a randomized controlled trial.

Aim: Evaluating the efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of Helicobacter pylori.

Background: Several probiotics such as Saccharomyces boulardii have been investigated for their clinical efficacy. This probiotic, inhibit H.

The effect of the treatment of Helicobacter pylori infection on the glycemic control in type 2 diabetes mellitus.

Aim: To evaluate the possible long-term effects of Helicobacter pylori infection on Hemoglobin A1c and fasting blood sugar levels in patients with type 2 diabetes.

Background: Helicobacter pylori causes the gastrointestinal tract inflammation, which it plays an important role in distortion of glucose and lipids absorption that altered lipid metabolism and energy harvesting and develops type 2 diabetes, insulin resistance and has been linked to impaired blood glucose.

Patients And Methods: In this clinical trial, patients with type 2 diabetes and confirmed Helicobacter pylori infection were recruited from the endocrinology clinic of the Shahid Beheshti University Tehran, Iran.

Evaluation of psychological aspects among subtypes of irritable bowel syndrome.

Context: While some studies have found disparities between subtypes of irritable bowel syndrome (IBS), others did not found such differences.

Aim: This study aimed to investigate whether there are differences in psychological features between the subtypes of IBS.

Settings And Design: A cross-sectional study was performed on all consecutive outpatients IBS diagnosed (from Oct.

Duodenal adenocarcinoma might be the cause of intractable nausea and vomiting in patient with coeliac disease.

Coeliac disease (CD) is an autoimmune disorder which leads to chronic inflammation of the gut. Untreated CD is associated with upper gastrointestinal malignancies, Small-bowel lymphoma and adenocarcinoma are recognized complications of untreated coeliac disease (CD). We report the case of a 43-year-old male suffering from CD who was treated with a gluten-free diet one year, presenting with complaints of intractable nausea and vomiting.

Non-Helicobacter pylori, non-NSAIDs peptic ulcers: a descriptive study on patients referred to Taleghani hospital with upper gastrointestinal bleeding.

Aim: The purpose of the present study was to evaluate the number and proportion of various causes of upper gastrointestinal bleeding and actual numbers of non-NSAID, non-Helicobacter pylori (H.pylori) peptic ulcers seen in endoscopy of these patients.

Background: The number and the proportion of patients with non- H.

A patient with chronic hepatitis C and a pancreatic mass in endoscopic ultrasound.

We report a rare case of pancreas tumor (lymphoma) in a patient with a history of chronic hepatitis C virus (HCV) infection without treatment, with a high viral load (20,199,805 IU/ml). He presented with abdominal pain, jaundice, weight loss and sweating. Computed tomography showed a hypodense mass located in the head of the pancreas, and immunohistochemistry of a specimen obtained by endoscopic ultrasound-guided fine needle aspiration revealed non-Hodgkin's lymphoma of the pancreas, B cell type.