Publications by authors named "Ghislaine Dujovne"

Article Synopsis
  • Early ultrasound examinations in pregnant mares are generally infrequent after initial diagnosis, but this case highlights the importance of ongoing monitoring.
  • A 17-year-old Thoroughbred mare carrying a mule fetus was extensively examined via transrectal ultrasound at 186 days of gestation, revealing multiple fetal abnormalities, including congenital cataracts and intrauterine growth restriction.
  • Ultimately, the pregnancy ended with an induced abortion at 272 days due to fetal complications, illustrating the effectiveness of ultrasound in diagnosing and managing equine fetal health issues.
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  • Transvaginal aspiration of oocytes (TVA) is a procedure used to collect oocytes in horses for embryo production, and this study aimed to assess its effects on blood and peritoneal parameters.
  • A total of 14 mares were evaluated before and 24 hours after TVA, with most remaining healthy; only one mare experienced mild temporary issues.
  • Significant changes were noted in leukograms and peritoneal fluid after the procedure, indicating a normal inflammatory response, with changes in lactate, total protein, and neutrophil counts serving as useful indicators of inflammation.
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  • The study focused on 24 mares with uterine prolapse treated from 1988 to 2019, exploring their predispositions and outcomes.
  • Key findings revealed that Arabian mares were more likely to experience uterine prolapse, as they made up a significant portion of the affected group compared to all mares treated.
  • Despite the medical interventions, 74% of the mares survived to discharge and no specific factors, such as age or number of births, were linked to their survival rates.
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Article Synopsis
  • The study aimed to replicate successful biobanking methods used on Thoroughbred mares, this time on two adult stallions under the FAANG initiative, involving comprehensive examinations before humane euthanasia.
  • After euthanasia, various biological samples, including sperm, skin biopsies, and fluids, were collected and preserved for further research and analysis.
  • Mild health abnormalities were identified in both stallions, and genomic resources from the samples will enhance equine genomic research, particularly in understanding tissue-specific gene regulation based on sex.
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Background: Granulosa cell tumours (GCT) are the most common ovarian tumours in mares. While the classical presentation may not represent diagnostic challenges, diagnosis is not easy in the early stages.

Objectives: Illustrate the variability in the presentation and serum biomarkers associated with ovarian abnormalities in the mare.

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Although exercise and acupuncture are frequently used therapies to treat persistent postbreeding endometritis, their efficacy to date is unproven. The objective of this study was to determine if exercise and acupuncture are effective methods to reduce intrauterine fluid and compare the effectiveness of these treatments to the use of uterine ecbolics. Twelve mares susceptible to postbreeding endometritis were enrolled in the study with a randomized cross-over design using both positive and negative controls.

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Placentitis has been reported as the most important cause of equine abortions, stillbirths, and perinatal deaths in horses. Most cases are caused by bacteria and less commonly by fungal elements. The aim of this report is to describe the clinical presentation of a fungal placentitis caused by Aspergillus terrerus.

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Chlorhexidine gluconate solution is a potent antimicrobial and therefore could be used effectively for treatment of endometritis, but historically this substance has been implicated as irritating to mucous membranes, including the endometrium of the mare. The use of chlorhexidine hydrochloride suspension (Nolvasan Suspension, Zoetis, Florham Park, NJ, USA) was evaluated in the uterus of normal mares to determine if adverse effects on endometrial health were noted. Twelve healthy, adult light breed mares were included in this study.

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A 25-year-old pregnant American Quarter Horse mare presented with a 1-week history of progressively worsening vaginal discharge. Transrectal ultrasound revealed increased thickness of the combined uterus and placenta with evidence of chorioallantoic edema but no placental separation. A thickened amnion was visible on transabdominal ultrasound.

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