Publications by authors named "Ghergie M"

Background: Inflammation-induced oxidative stress is a pathophysiological mechanism of inflammatory diseases. Treatments targeting oxidative stress can reduce inflammatory tissue damage.

Objectives: This study aimed to conduct phytochemical analysis and evaluate the antioxidant effects of the hydroalcoholic extract of blossoms () and rhizomes ().

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Article Synopsis
  • Irregularities in jaw development can cause skeletal malocclusion, a common issue impacting facial appearance, chewing, and speech, often needing orthodontic treatment or surgery.
  • This study explored the link between a specific genetic variant (SNP of the FBN3 gene) and malocclusion risks in 57 Romanian patients, finding that allele A is linked with Class II malocclusion, while allele G is linked with Class III.
  • Although genetic factors are involved, cephalometric analysis showed no significant differences among gene types, indicating further research with larger samples is necessary to fully understand these associations and any rare genetic variants influencing jaw development.
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Assessment of maxillary transverse discrepancy requires an accurate tool in order to implement the appropriate treatment plan. To evaluate the accuracy of Pont's Index in confirming a transverse maxillary deficiency by comparing its results with the corresponding results yielded by the University of Pennsylvania CBCT analysis. The study was performed on dental casts and CBCT's of 60 randomly selected patients by adopting a cluster sampling method.

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In the era of fixed appliances, some orthodontic practitioners seem to forget about functional therapy. Functional appliances are the only capable of orthopedically changes during the growth spurt. Activators of all types, classic or opened, are elected appliances in growing subjects with class II/1 anomalies.

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Correct breast feeding can be considered a tool for the post-natal prophylaxis of craniofacial abnormalities, or at least a way of reducing their extent. Inadequate bottle feeding forces the tongue and cheek muscles to develop a compensating and atypical function, in order to obtain the milk. As a result, there can be an adaptation change of the dental and bone structures, leading to malocclusions.

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In recent decades with the advancement of molecular research, information regarding specific molecular mechanisms has exploded. In the present review we present the molecular basis of dental pathologies that are of particular interest to clinicians.

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