Possible Involvement of Long Non-Coding RNAs and in the Modulation of 5-Fluorouracil Chemosensitivity in Colon Cancer Cells through Increased Extracellular Release of Exosomes.

A growing number of studies have suggested the involvement of long non-coding RNAs as the key players in not just the initiation and progression of the tumor microenvironment, but also in chemotherapy tolerance. In the present study, generated 5-FU-resistant SW480/DR cells were analyzed via cDNA microarray for its aberrant lncRNAs and mRNAs expression in comparison with the 5-FU-susceptible SW480/DS cells. Among the 126 lncRNAs described, lncRNAs , , and have been identified to be significantly upregulated, while lncRNs , , and have been found to be significantly downregulated.

Methicillin-Resistant from Peninsular Malaysian Animal Handlers: Molecular Profile, Antimicrobial Resistance, Immune Evasion Cluster and Genotypic Categorization.

() infections, particularly methicillin-resistant (MRSA) in humans and animals, have become a significant concern globally. The present study aimed to determine the prevalence and antibiogram of isolated from animal handlers in Peninsular Malaysia. Furthermore, the genotypic characteristics of isolates were also investigated.

Molecular detection and antibiogram of in rabbits, rabbit handlers, and rabbitry in Terengganu, Malaysia.

Objectives: This study aims to investigate the prevalence and antibiogram of and methicillin-resistance (MRSA) in rabbits, rabbit handlers, and rabbitry environments in Terengganu.

Materials And Methods: Swab samples from 183 rabbits (183 oral and 183 ear swabs), 45 rabbit handlers (45 oral and 45 nasal), and environmental ( = 180) samples from rabbitries were collected from 10 rabbit farms in Terengganu. The associated isolates from the swabs were isolated using phenotypic microbiology tests.

Nasal colonisation, antimicrobial susceptibility and genotypic pattern of Staphylococcus aureus among agricultural biotechnology students in Besut, Terengganu, east coast of Malaysia.

Background: This study aimed to profile the antimicrobial susceptibility and presence of resistance and virulence genes of methicillin-susceptible Staphylococcus aureus (MSSA) and MRSA nasal carriage, by means of genotypic analyses, in students of a tertiary institution in the state of Terengganu, east coast of Malaysia.

Methods: A total of 370 agricultural biotechnology students from Universiti Sultan Zainal Abidin in Besut, Terengganu, were enrolled in this study. Antimicrobial susceptibility profiles were evaluated by standard methods.