Spatial Distribution and Long-Term Persistence of -Infected in the Mentari Court, Malaysia.

Dengue is endemic in Malaysia, and vector control strategies are vital to reduce dengue transmission. The strain AlbB carried by both sexes of was released in Mentari Court, a high-rise residential site, in October 2017 and stopped after 20 weeks. frequencies are still being monitored at multiple traps across this site, providing an opportunity to examine the spatiotemporal distribution of and mosquito density with respect to year, residential block, and floor, using spatial interpolation in ArcGIS, GLMs, and contingency analyses.

strain AlbB maintains high density and dengue inhibition following introduction into a field population of .

mosquitoes carrying the AlbB strain show a reduced capacity to transmit dengue virus. AlbB has been introduced into wild populations in several field sites in Kuala Lumpur, Malaysia, where it has persisted at high frequency for more than 2 years and significantly reduced dengue incidence. Although these encouraging results indicate that AlbB releases can be an effective dengue control strategy, the long-term success depends on AlbB maintaining high population frequencies and virus transmission inhibition, and both could be compromised by host coevolution in the field.

Establishment of Wolbachia Strain wAlbB in Malaysian Populations of Aedes aegypti for Dengue Control.

Dengue has enormous health impacts globally. A novel approach to decrease dengue incidence involves the introduction of Wolbachia endosymbionts that block dengue virus transmission into populations of the primary vector mosquito, Aedes aegypti. The wMel Wolbachia strain has previously been trialed in open releases of Ae.