Publications by authors named "Ghasemzadeh M"

X-irradiation of blood products is an alternative for gamma-ray to prevent post-transfusion GvHD. However, commercial X-irradiators are not widely available while little is known about their safety and efficacy for platelet products. This study introduces an efficient, accessible and cost-effective "X irradiation system" for platelet concentrates (PCs).

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Mayonnaise is an oil-in-water emulsion with 65-85% oil, and its physicochemical and sensory characteristics are greatly influenced by the type of oil used. The nutritional value and oxidation resistance of oil (PAO) are very desirable due to the essential fatty acids (oleic and linoleic) and antioxidant compounds (phenolics and tocopherols). In this research, the physicochemical and sensory characteristics of mayonnaise sauce (MNS) with different levels of PAO (15% (MNS-PAO15%), 30% (MNS-PAO30%), and 100% (MNS-PAO), as a substitute for soybean oil (SBO)) were compared with sauces containing SBO with antioxidants (MNS-SBOA) or without antioxidants (MNS-SBO) during storage for 30 days at 25°C.

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During coronary artery bypass grafting (CABG), the surgical procedure, particularly the manipulation of the major arteries of the heart, induces a significant inflammatory state that may compromise platelet function to the extent that platelet transfusion is required. Given stored platelets as a major source of biological mediators, this study investigates the effects of platelet transfusion on the major pro-aggregatory, pro-inflammatory and immunomodulatory markers of platelets. Platelets from 20 patients, 10 who received platelet transfusion and 10 without, were subjected to flow cytometery where P-selectin and CD40 ligand (CD40L) expressions and PAC-1 binding (activation-specific anti GPIIb/GPIIIa antibody) analysed at five-time points of 24 h before surgery, immediately, 2 h, 24 h and 1 week after surgery.

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The presence of metronidazole (MNZ) and acetaminophen (ACE) in aquatic environments has raised growing concerns regarding their potential impact on human health. Incorporating various patterns into a photocatalytic material is considered a critical approach to achieving enhanced photocatalytic efficiency in the photocatalysis process. In this study, WO nanoparticles, which were immobilized onto ferromagnetic multi-walled carbon nanotubes that were functionalized using (3-glycidyloxypropyl)trimethoxysilane (FMMWCNTs@GLYMO@WO), exhibited remarkable efficiency in removing MNZ and ACE (93% and 97%) in only 15 min.

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Background: Platelet storage is complicated by deleterious changes, among which reduction of ristocetin-induced platelet aggregation (RIPA) has a poorly understood mechanism. The study elucidates the mechanistic roles of all the possible players in this process.

Research Design And Methods: PRP-platelet concentrates were subjected to RIPA, collagen-induced platelet aggregation (CIPA), and flowcytometric analysis of GPIbα and PAC-1 binding from days 0 to 5 of storage.

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Water sources have become extremely scarce and contaminated by organic and inorganic industrial and agricultural pollutants as well as household wastes. Poisoning water resources by dyes and metals is a problem because contaminated water can leak into subsurface and surface sources, causing serious contamination and health problems. Therefore, developing wastewater treatment technologies is valuable.

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Problem: Realizing that a child has a lifelong developmental condition like Autism Spectrum Disorder (ASD) can create feelings of sadness and grief for the parents. It remains unclear, however, how parents deal with and understand these emotions. The purpose of this narrative review was to explore the grief process of parents of children with ASD.

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In this report, we synthesized some pyrimidine derivatives by multi-component reaction of urea, benzaldehydes, and 1,3-indandione in the presence of ZIF-8/ZnFeO/GO-OSOH nanocomposite under reflux conditions. Initially, graphene oxide was prepared from graphite, and then it was sulfonated using ClOSOH. Next, GO-OSOH nanosheets were used to support ZIF-8/ZnFeO nanostructure.

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Background: Coronary artery bypass grafting (CABG) is considered the choice treatment for patients suffering from coronary artery disease (CAD). In the inflammatory milieu of cardiopulmonary bypass (CPB), systemic inflammatory response syndrome (SIRS) can induce a platelet pro-inflammatory state which could exacerbate post-CABG inflammatory status while affecting hemostatic function in patients. Therefore, focusing on platelets, the study presented here attempted to evaluate the pro-inflammatory and immunomodulatory profile of platelets as well as pro-aggregatory status during CABG.

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This study deals with preparing and characterizing polyvinyl alcohol/egg white/montmorillonite bionanocomposite hydrogels as antibacterial drug delivery systems. The cyclic freezing/thawing method was utilized to fabricate the hydrogels. To study the performance of the prepared hydrogels as drug delivery systems, amoxicillin, as a model antibiotic drug, was loaded into the hydrogels by mixing with the precursor polymer solution and gelation.

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The creation of an emerging porous structure using the hybridization of UiO-66-NH-MOF, a zirconium-based metal-organic framework (MOF), with a covalent organic framework (COF) based on terephthaldehyde and melamine (UiO-66-NH-MOF@COF), was assessed using SEM, XRD, EDX/mapping, FT-IR, BET, and TGA analyses. Using the obtained composite as a potential recoverable heterogeneous nanocatalyst, different aldehydes were condensed with isatoic anhydride and anilines or ammonium acetate under solvent-free conditions to create derivatives of 2,3-dihydroquinazolin-4(1)-one. Examining the catalytic capabilities of the designed UiO-66-NH-MOF@COF to efficiently produce 2,3-dihydroquinazolin-4(1)-ones was a standout activity.

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Herein, a new visible-light active exfoliated g-CN/γ-FeO/ZnO yolk-shell nanoparticles (NPs) was synthesized as a magnetically separable photocatalyst. For an in-depth understanding of the magnetic photocatalyst's structural, morphological, and optical properties, the products were extensively characterized with FT-IR, XRD, TEM, HRTEM, FESEM, EDS, EDS-mapping, VSM, DRS, EIS, and photocurrent. The photocatalyst was then utilized to degrade Levofloxacin (LEVO) and Indigo Carmine (IC) by visible light at room temperature.

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This study reports a facile and cost-effective technique for preparing magnetic copper ferrite nanoparticles supported on IRMOF-3/GO [IRMOF-3/GO/CuFeO]. The synthesized IRMOF-3/GO/CuFeO was characterized with IR, SEM, TGA, XRD, BET, EDX, VSM, and elemental mapping. The prepared catalyst revealed higher catalytic behavior in synthesizing heterocyclic compounds through a one-pot reaction between various aromatic aldehydes, diverse primary amines, malononitrile, and dimedone under ultrasound irradiations.

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The objective of the current study was to investigate the grief experiences of people affected by COVID-19. The study adopted a qualitative design of descriptive phenomenology. Fifteen adults who had lost a family member during the COVID-19 pandemic were selected as the sample through the purposive sampling method until theoretical saturation was achieved.

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Background: Although gamma-irradiation to platelet products is a standard method to prevent the risk of TA-GVHD in vulnerable recipients, it induces some proteomic and redox changes, of which irradiation-induced ROS increments may potentiate platelet mitochondrial dysfunction. However, whether these changes cause platelet apoptosis, or affect their viability during storage, is the main subject of this study.

Methods: PLT-rich plasma PC was split into two bags, one kept as control while other was subjected to gamma-irradiation.

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Biofilm formation and resistance to antibiotics in pathogenic bacteria are important concerns in the treatment of infectious diseases. A new rapid, eco-friendly and cost-effective strategy to overcome these problems is the use of microbial exopolysaccharides (EPS) for green synthesis of various metal nanoparticles (NPs). This study used EPS from a native probiotic Lactobacillus isolate to synthesize silver nanoparticles (AgNPs) with effective antimicrobial, antibiofilm and antioxidant properties.

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Background: HLA-E interaction with inhibitory receptor, NKG2A attenuates NK-mediated cytotoxicity. NKG2A overexpression by SARS-CoV-2 exhausts NK cells function, whereas virus-induced down-regulation of MHC-Ia reduces its derived-leader sequence peptide levels required for proper binding of HLA-E to NKG2A. This leads HLA-E to become more complex with viral antigens and delivers them to CD8 T cells, which facilitates cytolysis of infected cells.

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This paper reports the first investigation of the inverse finite element method (iFEM) coupled with the genetic algorithm (GA) to optimize sensor placement models of plate/shell structures for their real-time and full-field deformation reconstruction. The primary goal was to reduce the number of sensors in the iFEM models while maintaining the high accuracy of the displacement results. Here, GA was combined with the four-node quadrilateral inverse-shell elements (iQS4) as the genes inherited through generations to define the optimum positions of a specified number of sensors.

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Activated platelets are involved in the atherogenic stage of atherosclerosis, while they can also progress it to atherothrombosis which may cause an ischemic state and organ failure. In general, coronary artery disease (CAD) is considered as common and severe clinical consequence of atherosclerosis, manifesting as a chronic inflammatory condition with the release of platelet mediators, among which the importance of platelet-borne TGF-β1 is not yet well understood. Hence, for the first time, this study aimed to examine platelet level of TGF-β1 (latent/mature) in CAD-patients and its association with the expression of platelet pro-inflammatory molecules.

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The elimination of toxic and hazardous contaminants from different environmental media has become a global challenge, causing researchers to focus on the treatment of pollutants. Accordingly, the elimination of inorganic and organic pollutants using sustainable, effective, and low-cost heterogeneous catalysts is considered as one of the most essential routes for this aim. Thus, many efforts have been devoted to the synthesis of novel compounds and improving their catalytic performance.

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