Endothelial progenitor cells for fabrication of engineered vascular units and angiogenesis induction.

The promotion of vascularization and angiogenesis in the grafts is a crucial phenomenon in the healing process and tissue engineering. It has been shown that stem cells, especially endothelial progenitor cells (EPCs), can stimulate blood vessel formation inside the engineered hydrogels after being transplanted into the target sites. The incorporation of EPCs into the hydrogel can last the retention time, long-term survival, on-target delivery effects, migration and differentiation into mature endothelial cells.

Application of Artificial Intelligence in Tissue Engineering.

Tissue engineering, a crucial approach in medical research and clinical applications, aims to regenerate damaged organs. By combining stem cells, biochemical factors, and biomaterials, it encounters challenges in designing complex 3D structures. Artificial intelligence (AI) enhances tissue engineering through computational modeling, biomaterial design, cell culture optimization, and personalized medicine.

Oral Administration of Recombinant Expressing Ovalbumin-CPE Fusion Protein Induces Antibody Response in Mice.

, a subspecies of , is a well-known eukaryotic probiotic with many benefits for human health. In the present study, a recombinant strain of was prepared to use as a potential oral vaccine delivery vehicle. In this sense, a ura3 auxotroph strain of CNCM I-745 (known as HANSEN CBS 5926, Yomogi) was generated using CRISPR/Cas9 methodology.

Expression of neutrophil gelatinase-associated lipocalin (NGAL) in peripheral nerve repair.

Introduction: Trauma is one of the causes of peripheral nerve injuries. Free radicals increase after tissue damage. Free radicals are usually scavenged and detoxified by antioxidants.

Cellular immunity survey against urinary tract infection using pVAX/fimH cassette with mammalian and wild type codon usage as a DNA vaccine.

Purpose: FimH (the adhesion fragment of type 1 fimbriae) is implicated in uropathogenic Escherichia coli (UPEC) attachment to epithelial cells through interaction with mannose. Recently, some studies have found that UPEC can thrive intracellularly causing recurrent urinary tract infection (UTI). Almost all vaccines have been designed to induce antibodies against UPEC.

Evaluation of mammalian codon usage of fimH in DNA vaccine design.

Uropathogenic Escherichia coli (UPEC) bacteria are the principal cause of urinary tract infections (UTI). Because these bacteria propagate intracellularly, the cellular immune response is an important factor in UTIs. Therefore, we designed a genetic construct to induce a cellular immune response.