Publications by authors named "Gharib Ajob"
Background: Left ventricular assist device (LVAD)-associated infections are major complications that can lead to critical outcomes. The aims of this study were to assess the incidence of and to determine the risk factors for LVAD-associated infections.
Methods: We included all consecutive patients undergoing LVAD implantation between January 1, 2010, and January 1, 2019, in a single institution.
Article Synopsis
- Thromboembolic ischemic stroke (IS) is a serious risk following the placement of a left ventricular assist device (LVAD), complicating surgical treatment due to the use of anticoagulants.
- A 39-year-old man experienced cardiogenic shock and underwent LVAD placement, but developed acute neurological deficits indicative of IS, which was confirmed by a CT scan; he then underwent emergency decompressive hemicraniectomy.
- The case highlights that a careful approach to anticoagulation and teamwork in managing post-stroke care following LVAD surgery can lead to improved patient outcomes, including eventual heart transplantation.
Article Synopsis
- * RVF occurred in 32 patients (47.1%), with significant predictors being high preoperative vasoactive inotropic scores and serum glutamic oxaloacetic transaminase levels, while a thoracotomy approach significantly lowered RVF risk.
- * Mortality rates were high, with 53.1% in the RVF group vs. 5.6% in controls, and one-year survival rates were significantly better for the non-RVF group (85.4% vs. 33.5%).
In previously healthy persons suffering from acute illnesses, nosocomial infections (NIs) are frequent. Their prevalence suggests the existence of as yet unknown conditions that may promote care-related infection. This study assessed whether the measurement of plasma chromogranin A, a stress-related protein involved in innate defense, is related to NI risk, and whether any chromogranin A-derived fragment included in vasostatin-I displays immunosuppressive activities related to AP-1 or NF-kappa B downregulation.
View Article and Find Full Text PDFImpact of prosthesis-patient mismatch on early haemodynamic status after aortic valve replacement.
Interact Cardiovasc Thorac Surg
January 2017
Article Synopsis
- The study aimed to investigate how prosthesis-patient mismatch (PPM) affects early haemodynamic status and mortality in patients undergoing aortic valve replacement (AVR) for aortic stenosis (AS).
- It included 183 patients and found that PPM was present in about 28% of cases, but there were no significant differences in the vasoactive-inotropic dependency index (VDI) or other critical postoperative measurements between patients with and without PPM on the first days after surgery.
- The conclusions indicated that PPM does not significantly impact the early haemodynamic status or organ performance after AVR, suggesting that patients with PPM may not be at higher risk for complications in the immediate postoperative period.