Yellow phosphorus or metal phosphide (YP-MP) rodenticide poisoning has been a known cause of acute liver failure (ALF) in many countries of Asia and North and South America over the last decade. It is a highly toxic compound and is a well-known cause of intentional or accidental poisoning in both adults and children. In lower doses, it causes gastrointestinal symptoms and mild hepatic injury, and patients may spontaneously recover.
View Article and Find Full Text PDFBackground: Living donor liver transplantation (LDLT) has revolutionized the field of transplantation without compromising donor safety. Donor safety is of paramount concern to the transplant team. BMI >35 kg/m is mostly considered a contraindication to liver donation.
View Article and Find Full Text PDFBackground: The coronavirus disease 2019 (COVID-19) pandemic has brought about radical changes in our habits and lifestyles. The suspension of schools has led children to spend long hours at home, with reduced socialization, and changes in dietary patterns, oral hygiene practices and sleep routines. During a pandemic, appropriate oral health management and disease prevention are very important for the child's oral and general health.
View Article and Find Full Text PDFImportance: An outbreak of COVID-19-associated rhino-orbitocerebral mucormycosis (CAM) has occurred in many parts of the world. Although the clinical profile and risk factors for CAM have been studied, cumulative mortality and its risk factors have not.
Objective: To report the cumulative mortality rates at different times in cases with CAM and identify risk factors for CAM-associated mortality.
The COVID-19 pandemic has resulted in widespread use of complementary and alternative medicines. Tinospora cordifolia is a widely grown shrub which has been commonly used in India's traditional system of Ayurveda for its immune booster properties and has been extensively used as prophylaxis against COVID-19. Six patients (4 women, 2 men) with a median (IQR) age of 55 years (45-56) and with an history of Tinospora cordifolia consumption presented with symptoms of acute hepatitis during the study period of 4 months in the COVID-19 pandemic.
View Article and Find Full Text PDFUnlabelled: Many of the neurons in early visual cortex are selective for the orientation of boundaries defined by first-order cues (luminance) as well as second-order cues (contrast, texture). The neural circuit mechanism underlying this selectivity is still unclear, but some studies have proposed that it emerges from spatial nonlinearities of subcortical Y cells. To understand how inputs from the Y-cell pathway might be pooled to generate cue-invariant receptive fields, we recorded visual responses from single neurons in cat Area 18 using linear multielectrode arrays.
View Article and Find Full Text PDFBackground And Objectives: The behavior of odontogenic lesions varies with some tumors behaving like a cyst and some cysts behaving like tumors. p63, a member of the p53 family of tumor suppressor genes has recently come into light in view of its role as an oncogene. The aim of the present study was to investigate the expression of p63 protein in OKC, Solid ameloblastoma, Unicystic Ameloblastoma and Follicular tissue.
View Article and Find Full Text PDFBackground: Percutaneous endoscopic gastrostomy (PEG) is the procedure of choice for long-term enteral feeding.
Objective: This prospective observational study was carried out to compare the safety of commencing feeding 3 h compared to 16-24 h after PEG tube placement.
Methods: One hundred and ten patients with oropharyngeal malignancies who had consented for PEG were enrolled.
Pseudomelanosis duodeni is a rare, benign condition of unknown etiology. It is characterized by collection of pigment-laden macrophages in the tips of duodenal villi. The pigment, originally interpreted as melanin, pseudomelanin, lipomelanin or hemosiderin, has now been demonstrated to be mostly ferrous sulfide.
View Article and Find Full Text PDFRecent studies suggest that exposure to only one component of audiovisual events can lead to cross-modal cortical activation. However, it is not certain whether such crossmodal recruitment can occur in the absence of explicit conditioning, semantic factors, or long-term associations. A recent study demonstrated that crossmodal cortical recruitment can occur even after a brief exposure to bimodal stimuli without semantic association.
View Article and Find Full Text PDFFrom our daily experience, it is very clear that relative motion cues can contribute to correctly identifying object boundaries and perceiving depth. Motion-defined contours are not only generated by the motion of objects in a scene but also by the movement of an observer's head and body (motion parallax). However, the neural mechanism involved in detecting these contours is still unknown.
View Article and Find Full Text PDFUnlabelled: Guillain-Barre Syndrome (GBS) has an unpredictable clinical course with up to 30% of patients requiring assisted ventilation during the course of their illness. Successful management mandates anticipation, prompt recognition and optimal treatment of neuromuscular respiratory failure in GBS.
Aims: To identify clinical and electrodiagnostic predictors of neuromuscular respiratory paralysis in GBS.