Comparative Genome Analysis of 2 Strains from Pakistan: Insights Globally Into Drug Resistance, Virulence, and Niche Adaptation.

Multidrug-resistant is a global threat particularly in developing countries like Pakistan. In this study, we identified 2 strains, mnpk and swlpk, by 16S RNA genes, sequenced their draft genome, and compared the 2 genomes with reference strain H37Rv and gene expression analysis of selected virulent genes. Phylogenetic analysis of strains, mnpk and swlpk, using 16S RNA genes revealed that the strains are closely related with reference strain H37Rv.