Report: The effects of topical pleurotus tuberregium (PT) aqueous extract on intraocular pressure in monkeys.

Purpose: In earlier experiments in Nigeria, aqueous extract of Pleurotus tuber-regium (PT) had been shown to lower intra ocular pressure (IOP) in a feline model. The aim of the current study was to determine whether PT had the same or a similar IOP-lowering effect in ocularly normal non-human primates.

Methods: Four monkeys were treated twice daily for 4 days with 2 x 20 μl drops of 50 mg/ml PT (pH = 4.

The Royal King Culinary-Medicinal Mushroom, Pleurotus tuber-regium Sclerotium (Agaricomycetes), a Potential Source of Drug for Interocular Pressure Management.

Pleurotus tuber-regium has been reported to lower dexamethasone-induced ocular hypertension. Effects of P. tuber-regium and 0.

Contractile effect of aqueous Pleurotus tuberregium extract on the isolated bovine iris.

Background: Aqueous extract of Pleurotus tuberregium (PT) has been shown to reduce intraocular pressure (IOP) but the underlying mechanism has not been explained.

Purpose: To investigate the effect of PT on the bovine iris in vitro in comparison with acetylcholine (ACh).

Method: Strips of the iris were mounted in 10 ml organ baths and exposed to increasing concentrations of PT, ACh and a combination of both agents.