Accurate measurement tools are essential for evaluating the health-related quality of life in older adults. We aimed to translate and evaluate the psychometric properties of the Sickness Impact Profile-30 (SIP-30) in community-dwelling older adults. One hundred and fifty older adults participated in this study.
View Article and Find Full Text PDFBackground And Objectives: Though preventive measures are available to alleviate the burden of dental caries, there remain racial disparities in the utilization of preventative dental care. Our objectives were to determine whether racial disparities persisted in receiving preventive oral procedures between (1) black children and white children; and (2) Hispanic children and white children.
Methods: We used pooled Medical Expenditure Panel Survey data in the United States from 2018 to 2021.
Background: The role of physical activity (PA) monitoring during the recovery after orthopaedic surgeries is unclear. This study aimed to explore early changes in the pattern and level of PA following orthopedic surgeries.
Methods: This observational feasibility study included 11 hip replacement patients (four females) with a mean age of 66 years and five knee replacement patients (four females) with a mean age of 65 years.
Introduction: Toxoplasma gondii (T. gondii) infects all warm-blooded animals, including humans. Currently, no effective treatments exist to prevent the generation of chronic tissue cysts in infected hosts.
View Article and Find Full Text PDFThe purpose of our study was to use recent nationally-representative data to 1) determine whether reported adverse childhood experiences (ACEs) were associated with individual disordered eating behaviors (DEBs) for the US- based early and middle adolescent population; and 2) the extent to which individual ACE categories were associated with DEBs for this population. The study used cross-sectional data from the 2022 National Survey of Children's Health, which used parent-reported data. Inclusion criteria included all early (10-13 years of age) and middle-aged adolescents (14-17 years of age) (n = 24,173).
View Article and Find Full Text PDFThe reconstruction of MR images has always been a challenging inverse problem in medical imaging. Acceleration of MR scanning is of great importance for clinical research and cutting-edge applications. One of the primary efforts to achieve this is using compressed sensing (CS) theory.
View Article and Find Full Text PDFAnticancer immunotherapies with a dendritic Cell (DC) basis are becoming more popular. However, it has been suggested that the tumor's immunosuppressive mechanisms, such as inhibitory immunological checkpoint molecules, reduce the effectiveness of anticancer immunogenicity mediated by DC. Thus, overcoming immune checkpoints and inducing effective antigen-specific T-cell responses uniquely produced with malignant cells represent the key challenges.
View Article and Find Full Text PDFBackground: Hip and knee osteoarthritis (OA) patients demonstrate distinct gait patterns, yet detecting subtle abnormalities with wearable sensors remains uncertain. This study aimed to assess a predictive model's efficacy in distinguishing between hip and knee OA gait patterns using accelerometer data.
Method: Participants with hip or knee OA underwent overground walking assessments, recording lower limb accelerations for subsequent time and frequency domain analyses.
Objective: This scoping review aimed to identify and map how asynchronous digital two-way communication is used between patients and healthcare professionals after hospital discharge, as well as identify facilitators and barriers to implementation.
Methods: Following the JBI guidance for scoping reviews, we searched seven databases on August 29, 2022. Rayyan was employed for screening the articles, and data were extracted using a predefined and iteratively modified data extraction tool.
Developing bioequivalent (BE) generic products of complex dosage forms like intravitreal implants (IVIs) of corticosteroids such as dexamethasone prepared using hot-melt extrusion (HME), based on biodegradable poly (lactide-co-glycolide) (PLGA) polymers, can be challenging. A better understanding of the relationship between the physicochemical and physicomechanical properties of IVIs and their effect on drug release and ocular bioavailability is crucial to develop novel BE approaches. It is possible that the key physicochemical and physicomechanical properties of IVIs such as drug properties, implant surface roughness, mechanical strength and toughness, and implant erosion could vary for different compositions, resulting in changes in drug release.
View Article and Find Full Text PDFBackground: Almost half of patients with Crohn's disease (CD) require bowel surgeries in their lifetime. Due to the high risk of postoperative disease recurrence and high rate of previous antitumor necrosis factor (anti-TNF) failure, often alternative therapy options such as ustekinumab (UST) and vedolizumab (VDZ) are used. We aimed to evaluate the efficacy of UST and VDZ among postoperative CD patients as postoperative prophylaxis and rescue therapy.
View Article and Find Full Text PDFWe computationally and analytically investigate the plasmon near-field coupling phenomenon and the associated universal scaling behavior in a pair of coupled shifted-core coaxial nano-cavities. Each nano-cavity is composed of an InGaAsP gain medium sandwiched between a silver (Ag) core and an Ag shell. The evanescent coupling between the cavities lifts the degeneracy of the cut-off free transverse electromagnetic (TEM) like mode.
View Article and Find Full Text PDFThe purpose of the study was to determine whether visiting only a pediatric dentist (as opposed to visiting only a general dentist) was associated with the provision of preventive dental services for a U.S.-based pediatric population (those 18 years and younger).
View Article and Find Full Text PDFBackground: One of the most crucial objectives of policymakers is to enhance the population's overall health. Establishing a surveillance system is a way to achieve this goal. The Behavioral Risk Factor Surveillance System (BRFSS) is a national system that collects data on the health-related behaviors of the United States residents using the Behavioral Risk Factor Questionnaire (BRFSSQ).
View Article and Find Full Text PDFObjective: This study aims to assess the familial aggregation of traffic risky behaviours among pedestrians and describe the sociodemographic profile of pedestrians in northwestern Iran.
Methods: A cross-sectional study was conducted among 933 pedestrians in 2023. Participants were selected using stratified random sampling.
Purpose: Infection by the intracellular apicomplexan parasite has serious clinical consequences in humans and veterinarians around the world. Although about a third of the world's population is infected with , there is still no effective vaccine against this disease. The aim of this study was to develop and evaluate a multimeric vaccine against using the proteins calcium-dependent protein kinase (CDPK)1, CDPK2, CDPK3, and CDPK5.
View Article and Find Full Text PDFIgG4-related disease (IgG4-RD) is a chronic systemic inflammatory disease, characterized by tissue infiltration of lymphocytes and IgG4-secreting plasma cells, presenting by fibrosis of different tissues, which is usually responsive only to oral steroids therapy. Kidneys are the most commonly involved organs, exhibiting renal insufficiency, tubulointerstitial nephritis, and glomerulonephritis. Here, we describe a patient with acute renal insufficiency who was presented with edema, weakness, anemia and multiple lymphadenopathies.
View Article and Find Full Text PDFSpecific industrial or research applications necessitate specialized displacement measurement conditions, thereby driving researchers to innovate sensors based on novel operating principles. One such challenging condition is the prevalence of strong electromagnetic waves, which precludes using any sensor with a metallic structure or one that operates on electrical measurement principles. Additionally, space constraints in applications requiring multidimensional displacement measurements mandate the development of sensors capable of measuring displacements simultaneously in multiple directions.
View Article and Find Full Text PDFIn this paper, we propose a fractional-order mathematical model to explain the role of glucagon in maintaining the glucose level in the human body by using a generalised form of a fractal fractional operator. The existence, boundedness, and positivity of the results are constructed by fixed point theory and the Lipschitz condition for the biological feasibility of the system. Also, global stability analysis with Lyapunov's first derivative functions is treated.
View Article and Find Full Text PDFIntroduction: Continuous peripheral nerve blocks (cPNBs) have shown favourable post-operative pain control results but may be associated with a risk for long-term neurological complications. This study sought to examine factors associated with persistent post-operative pain and potential neuropathy after orthopaedic lower-limb surgery with the use of post-operative cPNB.
Methods: Patients who underwent lower limb orthopaedic procedures with cPNBs between November 2021 to May 2022 were included.
The study investigated the spatiotemporal relationship between surface hydrological variables and groundwater quality/quantity using geostatistical and AI tools. AI models were developed to estimate groundwater quality from ground-based measurements and remote sensing images, reducing reliance on laboratory testing. Different Kriging techniques were employed to map ground-based measurements and fill data gaps.
View Article and Find Full Text PDFBackground: Tetralogy of Fallot is the most prevalent cyanotic CHD. With the advent of advanced surgical methods, the majority of tetralogy of Fallot patients reach adulthood. However, many need re-intervention for the residual anomalies including residual right ventricular outflow obstruction, pulmonary regurgitation, residual ventricular septal defects, and progressive aortic dilatation.
View Article and Find Full Text PDFElectromagnetic pollution and cancer are phenomena that essentially endanger the future of humanity. Herein, multiple approaches are being proposed to solve the aforementioned issues. Recent studies have demonstrated that by regulating the morphology, defect, and phase of materials, their microwave absorbing, optical, and hyperthermia properties are tunable.
View Article and Find Full Text PDFObjective: Hand and upper limb functional impairments following stroke lead to limitations in performing activities of daily living. We aimed to investigate feasibility and efficacy of an early sensory-motor rehabilitation program on hand and upper limb function in patients with acute stroke.
Design: A pilot, single-subject experimental, A-B-A study.