Publications by authors named "Ghaedi A"
Introduction: Recent evidence suggests the relationship between periodontitis and systemic inflammation, which complete blood count can assess (CBC)-derived biomarkers such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR). We conducted this meta-analysis to evaluate the levels of NLR and PLR of patients with periodontitis compared to those of healthy controls. METHODS: Web of Science, PubMed, ProQuest, Scopus, and Open Grey were searched for studies published before October 20, 2024, without any limitation on date and language; then, using the random-effects model, we reported a standardized mean difference (SMD) with a 95% confidence interval (CI).
View Article and Find Full Text PDFBackground: We aimed to determine the association of neutrophil-to-lymphocyte ratio (NLR) with non-arteritic anterior ischemic optic neuropathy (NAION).
Methods: We conducted a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Scopus and Web of Science were searched from the establishment of the database to May 5, 2022 to find the relevant studies.
Background: Diabetes mellitus (DM), a worldwide disease affecting more than 400 million people, is associated with high blood pressure (BP). In addition to macrovascular complications, high BP in DM patients is potentially linked to microvascular complications. More than 70% of DM patients have retinopathy.
View Article and Find Full Text PDFBackground: Uncontrolled bleeding is still the major factor leading to preventable deaths following trauma. This study sought to assess the effectiveness of mini sponge-based wound stasis, cellulose-based local hemostatic, and traditional gauze dressings for the control of hemorrhages resulting from grade 4 liver injuries in rats.
Methods: Thirty Sprague-Dawley rats were divided into three equal groups.
Article Synopsis
- A new nano platform for phototherapy using natural materials has been developed, incorporating calcium carbonate nanoparticles from squid bones, dye from Syzygium cumini, and the chemotherapy drug Doxorubicin.
- Copper nanoparticles were added to enhance the effectiveness of the treatment, which uses an 808 nm laser for irradiation.
- The results indicate that this nano-composite is highly effective in generating reactive oxygen species and significantly raises temperature during treatment, showing promise for reducing toxicity and improving cancer therapy outcomes.
Diagnostic and prognostic role of NLR in testicular cancer.
Explor Target Antitumor Ther
September 2024
Article Synopsis
- - The study investigated the neutrophil to lymphocyte ratio (NLR) and its implications in testicular cancer, finding that NLR is higher in patients than in healthy individuals or those with benign conditions.
- - Post-surgery, specifically after orchiectomy, NLR levels significantly decrease, indicating a potential response to treatment.
- - An elevated NLR is associated with several negative prognostic factors, such as advanced cancer stage and poorer outcomes, although it cannot distinguish between different types of testicular cancer.
Background: Limb ischemia is a severe vascular condition that can lead to critical complications, endangering both limbs and lives. The goal of this research was to explore the role of neutrophil to lymphocyte ratio (NLR) in limb ischemia.
Methods: From inception to June 8, 2022, PubMed/MEDLINE, Institute for Scientific Information Web of Science, and Scopus were searched for articles comparing NLR in limb ischemia to healthy individuals.
Background: Giant coronary artery aneurysms (GCAA), are rare findings often discovered incidentally in adults. GCAAs are defined by a significant enlargement of coronary arteries, posing a heightened risk of myocardial infarction and thrombosis.
Case Presentation: A 52-year-old male known case of ischemic heart disease (IHD), presented with chest pain and signs of anterior ST-elevation MI (STEMI).
Article Synopsis
- The study aimed to assess how the neutrophil to lymphocyte ratio (NLR) impacts the outcomes of patients with penile squamous cell carcinoma (PSCC).
- A meta-analysis was performed, analyzing 14 studies to understand the relationship between NLR levels and patient survival, utilizing established quality assessment criteria.
- Results indicated that higher NLR levels were linked to worse prognosis and lower survival rates in PSCC patients, confirming NLR's important role in diagnosis and prognosis despite no link to tumor size or stage.
Article Synopsis
- Most traumatic lung injuries are typically treated non-operatively, but this study focuses on understanding survival rates for patients needing surgery for lung injuries on a nationwide scale.
- The study analyzed data from 170,377 trauma patients, revealing that only 2,159 (about 1.3%) required surgical intervention, with various types of surgery performed, including wedge resections, lobectomies, and pneumonectomies.
- The overall mortality rate for these surgical patients was 30%, with higher rates for more extensive surgeries like pneumonectomy; predictors of mortality included hilar injuries, age, and existing head and abdominal injuries.
Background: Optimal utilization of vasopressors during early post-injury resuscitation remains unclear. Our study aims to describe the relationship between the timing of vasopressor administration and outcomes among hypotensive trauma patients.
Methods: This was a retrospective analysis of the 2017-2018 ACS-TQIP database.
Background: Malnutrition is shown to be associated with worse outcomes among surgical patients, yet its postdischarge outcomes in trauma patients are not clear. This study aimed to evaluate both index admission and postdischarge outcomes of geriatric trauma patients who are at risk of poor nutritional status.
Methods: This is a secondary analysis of the prospective observational American Association of Surgery for Trauma Frailty Multi-institutional Trial.
Purpose: In a simulated situation of simultaneous spleen and liver trauma, we aimed to compare the outcomes of treating both injuries with spleen autotransplantation on the omentum (SAO) alongside hepatorrhaphy versus spleen autotransplantation as a patch on the liver parenchyma.
Methods: A total of 24 rats were separated into two groups: the SAO and the spleen autotransplantation on the liver. They underwent a uniform and simultaneous procedure involving full-thickness injuries to the left lobe of the liver and grade 4 spleen injuries.
Introduction: This study aims to evaluate the temporal trends of mortality among frail versus non-frail older adult trauma patients during index hospitalization.
Methods: We performed a 3-year (2017-2019) analysis of ACS-TQIP. We included all older adult (age ≥65 years) trauma patients.
Introduction: In the current systematic review and meta-analysis, we aim to analyze the existing literature to evaluate the role of inflammatory biomarkers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein (CRP), tumor necrosis factor-a (TNF-a), and interleukin-6 (IL-6) among individuals with cardiac syndrome X (CSX) compared to healthy controls.
Methods: We used PubMed, Web of Science, Scopus, Science Direct, and Embase to systematically search relevant publications published before April 2, 2023. We performed the meta-analysis using Stata 11.
Introduction: The inflammatory response to burn injuries can lead to organ dysfunction that ultimately results in increased mortality and morbidity. This meta-analysis was conducted to determine the efficacy of inflammatory biomarkers, including the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), procalcitonin (PCT), and C-reactive protein (CRP) as predictive tools of mortality among burn patients.
Material And Methods: The biomarker levels of survivors and non-survivors were consolidated according to guidelines for Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).
Meta-analysis of the Relationship Between Neutrophil to Lymphocyte Ratio and Nasal Polyps.
Indian J Otolaryngol Head Neck Surg
April 2024
Our study aimed to enhance understanding of nasal polyp pathophysiology by reviewing the data for variations of NLR values between patients with nasal polyp and healthy controls. We searched Web of Science, PubMed, ProQuest, and Scopus up to 2 April 2023. The search strategy was not limited to any specific language.
View Article and Find Full Text PDFBackground: We conducted this systematic review to compile the evidence for the role of neutrophil to lymphocyte ratio (NLR) in odontogenic infection (OI) and to determine whether NLR is elevated in patients with OI. This was done to aid physicians in better understanding this condition for clinical management.
Methods: The search was conducted on PubMed, Scopus, and Web of Science libraries on March 30, 2023.
This meta-analysis assessed the use of the neutrophil-to-lymphocyte ratio (NLR) as a means of early detection of contrast-induced nephropathy (CIN) following diagnostic or therapeutic procedures. We used Web of Science, PubMed, and Scopus to conduct a systematic search. There was no limitation regarding language or date of publication.
View Article and Find Full Text PDFBackground: We conducted a systematic review and meta-analysis to compare the neutrophil lymphocyte ratio (NLR) levels between women with post-menopausal osteopenia or osteoporosis to those with normal bone mineral density (BMD).
Methods: We used Web of Science, PubMed, and Scopus to conduct a systematic search for relevant publications published before June 19, 2022, only in English language. We reported standardized mean difference (SMD) with a 95% confidence interval (CI).
Prognostic Role of Neutrophil to Lymphocyte Ratio in Allergic Rhinitis: A Systematic Review and Meta-analysis.
Indian J Otolaryngol Head Neck Surg
February 2024
Unlabelled: One of the crucial triggers of allergic diseases is an inflammatory reaction and neutrophil to lymphocyte ratio (NLR) is one of the systemic inflammation biomarkers. Our review aimed to evaluate role of NLR in predicting severity and comorbidities of allergic rhinitis (AR). We systematically searched Scopus, Web of Science, and PubMed to find relevant studies.
View Article and Find Full Text PDFIntroduction: Recurrent aphthous stomatitis (RAS) is a prevalent ulcerative condition affecting oral mucosa.
Objectives: A systematic review and meta-analysis was performed to compare the level of neutrophil to lymphocyte ratio (NLR) between individuals with RAS and those who are healthy.
Methods: A systematic search for relevant publications before June 21, 2022, was conducted using Web of Science, PubMed, and Scopus.
Article Synopsis
- The study investigates the relationship between the pre-operative neutrophil to lymphocyte ratio (NLR) in gastrointestinal surgery patients and the occurrence of anastomotic leaks (AL).
- A systematic review and meta-analysis included 12 studies with nearly 3,000 participants, revealing that those with AL had significantly higher NLR levels compared to those without.
- Subgroup analysis indicated that while retrospective studies showed a strong correlation, prospective studies did not, and the association varied by ethnicity, being significant for white patients but not for East Asian patients.