Publications by authors named "Ghadeer Alhendi"
Front Med (Lausanne)
December 2021
Article Synopsis
- Anti-drug antibodies (ATI for infliximab and ATA for adalimumab) negatively impact the effectiveness of anti-TNF therapy in patients with inflammatory bowel disease (IBD).
- A study analyzed data from 1,093 IBD patients across seven hospitals to examine the effects of patient sex on the levels of these antibodies and drug concentrations over a three-year period.
- Results indicated that males on infliximab had significantly higher anti-drug antibody levels and lower drug concentrations than females, while no differences were found in adalimumab efficacy between sexes or in combination therapy contexts.
Front Med (Lausanne)
September 2021
Article Synopsis
- * A study evaluated how well gastroenterologists adhered to anti-TNF combination therapy, revealing younger doctors and those interested in IBD were more likely to prescribe these therapies than their older or less interested counterparts.
- * Results showed that the younger gastroenterologists had a significantly higher percentage of patients on combination therapy for both infliximab and adalimumab, and they also requested more antibody level tests, highlighting differences in practice patterns based on age and interest in IBD.
