Publications by authors named "Ghada Mostafa Badawy"
Investigation of metronidazole resistance-associated mutations and virulence genotypes in helicobacter pylori isolates from the Egyptian population: A cross-sectional study.
Mohamed S Hemeda Heba A Elsayed ALMoatazbellah Mahmoud Elsayed Mohamad Moustafa M Ibrahim Alsayed Magdi Alsayed Farahat Ghada Mostafa Badawy
J Infect Chemother
February 2025
Article Synopsis
- This study investigates metronidazole resistance and virulence genotypes in H. pylori from Egyptian patients, highlighting the public health issue of antibiotic resistance in this bacterium.
- The research involved collecting gastric biopsies from 250 symptomatic patients and using molecular techniques to analyze antibiotic resistance mutations and virulence factors.
- Findings showed that 43.6% of H. pylori isolates were resistant to metronidazole, with significant links between resistance and virulence genes, suggesting that genetic factors may contribute to how the bacteria resist treatment.