The controverted therapeutic efficacy of Allium sativum and Artemisia herba-alba extracts on Cryptosporidium-infected mice.

Introduction: Cryptosporidiosis has become an issue of great interest being life-threatening among immunocompromised hosts worldwide. This study explored the curative effect of Allium sativum (garlic) and Artemisia herba-alba ethanolic extract versus Nitazoxanide drug on both immunocompetent and immunosuppressed-Cryptosporidium experimentally-infected mice.

Methodology: One hundred male Swiss albino mice were divided into the following groups: (GI) non-infected non-treated group, (GII) infected non-treated group, (GIII) garlic treated group, (GIV) A.

The potential therapeutic effect of and extracts versus Nitazoxanide drug against experimentally induced cryptosporidiosis in laboratory mice.

In this study, the potential anti-cryptosporidial effect of (black seeds) and (ginger) alcoholic extracts versus Nitazoxanide (NTZ) medication was investigated in immunosuppressed (IS) laboratory mice. Parasitological, histopathological studies were used to assess their therapeutic efficacy. Serum level and tissue expression percentage of IFN-γ was also used.

A novel no-sensors 3D model reconstruction from monocular video frames for a dynamic environment.

Occlusion awareness is one of the most challenging problems in several fields such as multimedia, remote sensing, computer vision, and computer graphics. Realistic interaction applications are suffering from dealing with occlusion and collision problems in a dynamic environment. Creating dense 3D reconstruction methods is the best solution to solve this issue.

Effect of nanoparticles on the therapeutic efficacy of praziquantel against infection in murine models.

Praziquantel (PZQ) is the main treatment of Schistosomiasis mansoni. However, resistance to it was described. So, there is a necessity to develop novel drugs or to enhance the present drugs.

Therapeutic potential effect of bone marrow-derived mesenchymal stem cells on chronic liver disease in murine .

Some reports have shown that mesenchymal stem cells (MSCs) therapy could ameliorate chemically-induced hepatic fibrosis. This research assesses the therapeutic action of bone marrow mesenchymal stem cells (BM-MSCs) on chronic diseased liver in infected mice. All infected female mice divided into three groups, one group (15 mice) treated with oral praziquantel (PZQ), second group (15 mice) received intravenous injection of BM-MSCs and third group (15 mice) treated with both MSCs + PZQ.

The impact of anthelminthic therapeutics on serological and tissues apoptotic changes induced by experimental trichinosis.

Trichinosis is a sharable parasitic disease caused by spp., the disease occurred on eating inappropriate cooked pork infected by the parasite encysted larvae. This study aimed to evaluate experimentally the impact of treatment by thiabendazole, praziquantel (PZQ) and prednisone on induced parasitological, serological and apoptotic changes.

Assessment of spiramycin-loaded chitosan nanoparticles treatment on acute and chronic toxoplasmosis in mice.

Toxoplasmosis is a zoonotic parasitic disease with worldwide distribution. Chitosan is a natural polymer which is commonly used in the production of nanomedicines. It is known to enable higher drug permeation, being biocompatible and has very low toxicity, besides its antimicrobial effects.

HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL STUDIES IN EXPERIMENTAL HETEROPHYIASIS AND THE ROLE OF PRAZIQUANTEL AND AMINOGUANIDINE.

Histopathological diagnosis was used to understand the pathological events associated with Heterophyes heterophyes (H. heterophyes) infection. CD3 and CD79α antibodies had been used as markers for both T and.

IMMUNOGENICITY ASSESSMENT FOR LUNG-STAGE AND BIOMPHALARIA ALEXANDRINA COCKTAIIVACCINE IN SCHISTOSOMA MANSONI INFECTED MICE.

Unlabelled: The availability of a new vaccine is usually needed as an additional component to chemotherapy for control of schistosomiasis. Different strategies of different types of vaccines were assessed to decrease morbidity but did not give the best protection. The study assessed the efficacy of BAAP, SLAP and their combined preparations together with BCG adjuvant as an effective anti-schistosomal vaccine.

COMPARISON OF IMMUNOCHROMATOGRAPHIC TEST AND MICROSCOPY IN THE DETECTION OF SOME ENTERIC PROTOZOA IN STOOL SAMPLES.

Infection with pathogenic intestinal protozoa. as Giardia lamblia,, Entamoeba histolytica and Cryptosporidium parvum cause considerable gastrointestinal morbidity, malnutrition and mortality worldwide, especially among young children in developing countries. The present study was carried out on 71 cases (44 males & 27 females) chosen from Pediatric and Internal Medicine Inpatient and Outpatient Clinics of Zagazig University Hospitals, complaining of different gastrointestinal troubles with an age range of 6-60 years.

Cytokine patterns in experimental schistosomiasis mansoni infected mice treated with silymarin.

The purpose of this study was to determine cytokine patterns in experimental schistosomiasis mansoni infected mice treated with silymarin. The study was conducted upon 100 mice that were divided into five groups; 20 each: uninfected control group, Schistosoma mansoni infected untreated mice (infected control), infected mice treated with praziquantel (PZQ), infected mice treated with silymarin and infected mice treated with both praziquantel and silymarin. 10 mice from each group were sacrificed at 10th and 18th weeks post infection respectively.

Geohelminths distribution as affected by soil properties, physicochemical factors and climate in Sharkyia governorate Egypt.

Soil-transmitted helminths are mainly a group of parasitic nematodes causing human infection through contact with parasite eggs or larvae; they survive in the warm and moist soil of the tropical and subtropical countries. This study was carried out in Sharkyia governorate from October, 2011 to October, 2013, to correlate between the prevalence and distribution of these parasites in the soil and the physicochemical factors affecting the examined samples of the soil. One hundred and twenty samples of different types of soil (clay, silt, sand) from different localities were collected and examined.

Relationship between serum cytokines profiles and hepatic fibrosis in schistosomiasis mansoni: an experimental study.

Forty of eighty mice (10 each group) were infected with S. mansoni cercariae and sacrificed at 3 weeks (G-A), 6 weeks (G-B), 12 weeks (G-C) and 16 weeks (G-D) post infection (P.I).