Publications by authors named "Gexue Lu"

Article Synopsis
  • * RNA-sequencing indicated that an HMD led to increased lipid synthesis, cholesterol metabolism, and inflammation-related pathways in the liver.
  • * Gut microbial analysis showed harmful shifts in the microbiome and decreased levels of beneficial bioactive lipids, suggesting that while methionine is necessary, too much can harm gut and liver health.
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Diet is a key player in gut-liver axis. However, the effect of different dietary patterns on gut microbiota and liver functions remains unclear. Here, we used rodent standard chow and purified diet to mimic two common human dietary patterns: grain and plant-based diet and refined-food-based diet, respectively and explored their impacts on gut microbiota and liver.

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belongs to Sulfate-reducing bacteria (SRB), which are widely present in anaerobic environments, including the human gut. has been associated with many human diseases, including chronic liver disease. However, the characteristics and difference of from fecal samples of healthy volunteers (HV) and patients with liver cirrhosis (LC) have not been fully elucidated.

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