Objectives: This study aimed to evaluate cardiac autonomic modulation using short-term heart rate variability (HRV) and compare it among frailty statuses in older Indian adults.
Methods: A total of 210 subjects aged 60 years and above were recruited into three groups: frail ( = 70), pre-frail ( = 70), and non-frail ( = 70) from the outpatient department of Geriatric Medicine at a tertiary care hospital in India. Frailty status was assessed using the Rockwood frailty index (FI) criteria.
Background Most elderly patients suffer from multiple diseases and are on multiple drugs for treatment. Polypharmacy in the elderly, physiological changes with old age, changes in the pharmacokinetics and pharmacodynamic effects of many drugs, and newer drug prescription trends for diseases like diabetes and cardiovascular disease make drug prescribing in the elderly more difficult. There are many chances of drug-drug interactions with easily available over-the-counter (OTC) medications.
View Article and Find Full Text PDFObjective: To estimate frailty prevalence and its relationship with the socio-economic and regional factors and health care outcomes.
Methods: In this study, participants from the harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) were included. The frailty index (FI) was calculated using a 32-variable deficit model, with a value of ≥ 25% considered as frail.
Primary systemic amyloidosis is an uncommon disease which presents with involvement of the kidney, heart, peripheral nervous system and liver. The involvement of skeletal muscles called amyloid myopathy is uncommon. We report a 74-year-old male who presented with progressively drooping shoulders followed by other muscular involvement without other organ involvement as a manifestation of amyloidosis.
View Article and Find Full Text PDFObjective: Muscle strength in older adults is usually measured according to grip strength, which demonstrates upper muscle strength only. In this study, we used one-repetition-maximum (1-RM) knee extension as a measure of lower limb strength and assessed its relationship with grip strength and various geriatric syndromes.
Methods: One hundred outpatients over the age of 65 years were recruited from a geriatric medicine center in India.