Bedside visualisation tool for prediction of deviation from intended dosage in multi-infusion therapy.

Background: In multi-infusion therapy, multiple infusion pumps are connected to one single vascular access point. Interaction between pressure changes from different pumps may result in temporary dosing errors, which can be very harmful to the patient. It is known that these dosing errors occur.

Unexpected dosing errors due to air bubbles in infusion lines with and without air filters.

The effect of the presence of an air bubble, inside an infusion line, on the time (Tnew) needed for a new medication to reach the patient after a syringe exchange was studied in this paper. If an air bubble escapes through an air filter, then a sudden drop in pressure occurs, causing a relaxation of the compressible part of the syringe, followed by a gradual restoration of the flow rate in the line. We modeled this phenomenon mathematically and measured it experimentally .

Effect of non-return valves on the time-of-arrival of new medication in a patient after syringe exchange in an infusion set-up.

The presence of a non-return valve in an infusion set-up is expected to affect the time-of-arrival of new medication in a patient after syringe exchange. Using Computational Fluid Dynamics (CFD) we have studied the flow through a typical non-return valve, focusing on two separate effects: (A) the overall delay in the time-of-arrival, and (B) timing effects due to the distortion of the Poiseuille flow profile in the non-return valve. The results show that (A) the additional delay in time-of-arrival of new medication, caused by the non-return valve alone, corresponds to the delay that would be caused by 11.

Contemporary management of patients with atrial fibrillation in the Netherlands and Belgium: a report from the EORP-AF long-term general registry.

Background: Contemporary data regarding the characteristics, treatment and outcomes of patients with atrial fibrillation (AF) are needed. We aimed to assess these data and guideline adherence in the EURObservational Research Programme on Atrial Fibrillation (EORP-AF) long-term general registry.

Methods: We analysed 967 patients from the EORP-AF long-term general registry included in the Netherlands and Belgium from 2013 to 2016.

Industry 4.0 Lean Shopfloor Management Characterization Using EEG Sensors and Deep Learning.

Achieving the shift towards Industry 4.0 is only feasible through the active integration of the shopfloor into the transformation process. Several shopfloor management (SM) systems can aid this conversion.

Deep Learning for Industrial Computer Vision Quality Control in the Printing Industry 4.0.

Rapid and accurate industrial inspection to ensure the highest quality standards at a competitive price is one of the biggest challenges in the manufacturing industry. This paper shows an application of how a Deep Learning soft sensor application can be combined with a high-resolution optical quality control camera to increase the accuracy and reduce the cost of an industrial visual inspection process in the Printing Industry 4.0.

Propensity of gynaecologists towards osteoporosis management and treatment.

Background: Regulation authorities have recently advised against the use of hormone replacement therapy (HRT) as a first choice treatment for postmenopausal osteoporosis, modifying the past consensus.

Aim: Analyse the sensibility to and prescription attitude for osteoporosis.

Setting: Survey.

[Avoidable visual impairment in The Netherlands: the project "Vision 2020 Netherlands" of the World Health Organization].

In the year 2004 there were an estimated 220,000-320,000 people in The Netherlands with visual impairment. In 150,000-220,000 (70%) of them the visual impairment is either curable or could have been prevented. Those most at risk are people with intellectual disabilities, elderly people in care institutions, elderly people in general and diabetics.

Estrogen therapy in older patients with recurrent urinary tract infections: a review.

Although urogenital complaints, such as recurrent lower urinary tract infections (UTI), and dysuria, are commonly encountered in elderly women, few women have participated in randomized studies of estrogen therapy for this condition. This is a paradox in view of the often cited beneficial effect of estrogen in reducing the incidence of UTI. Present evidence documents that in postmenopausal women, hormone replacement therapy using topical estrogen normalizes the vaginal flora and greatly reduces the risk of vaginal atrophy.

Magnetic resonance imaging in acute myocarditis: a case report and a review of literature.

We report a case of acute myocarditis in a 20-year-old male, suggested by the clinical picture, elevated cardiac enzymes, electrocardiography and serology. Diagnosis was confirmed by gadolinium-enhanced MRI showing part of the myocardium affected by an infiltrate. Impaired LV function and wall motion abnormalities were documented by echocardiography and FFE MRI.

Return to fertility in nulliparous and parous women after removal of the GyneFix intrauterine contraceptive system.

Objective: To evaluate the return to fertility following removal of the GyneFix intrauterine implant system in women wishing to conceive.

Study Design: A retrospective study was performed on a sample of healthy, sexually active nulligravid/nulliparous and parous women. The participants were 18-41 years of age, with no apparent infertility problem, living in a stable relationship and planning to become pregnant.

[Fainting caused by a neck tumor].

An 86-year-old woman was admitted with progressive complaints of dizziness and the sensation of losing consciousness several times a day; this had led her to fall down on a few occasions. The patient had experienced these symptoms for a month prior to admission. Two weeks before admission her family had noticed a swelling on the left side of her neck.

Decrease of bone mineral density during estrogen substitution therapy.

A decrease in bone mineral density (BMD) in patients treated with hormone replacement therapy (HRT) is sometimes observed in clinical practice. In order to assess the frequency and the characteristics of these cases, we reviewed the data of 102 women treated with HRT for more than 2 years, and who had undergone at least 3 lumbar BMD measurements during that period. For each patient, a linear function was fitted to the BMD data in relation to time.